Durite Plus 50mg/20mg Tablet


Product Info

Prescription required Yes
Marketer Leeford Healthcare Ltd
Active Ingredient Spironolactone (50mg) + Torasemide (20mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassCARDIAC
User Rating4.4
User Reviews403

FAQ

Question
Can the use of Durite Plus 50mg/20mg cause dehydration (excessive loss of fluid)?
Yes, the use of Durite Plus 50mg/20mg can cause dehydration (excessive loss of fluid). The patient may experience dryness of the mouth, thirst, drowsiness, restlessness, muscle pain, weakness, tiredness, fall in blood pressure (hypotension), decreased urination (oliguria), increased heart rate (tachycardia), nausea and vomiting. Inform your doctor if you experience persistent problems while taking this medicine.
Answer

Question
Can the use of Durite Plus 50mg/20mg cause gout?
Yes, Durite Plus 50mg/20mg can cause gout. Durite Plus 50mg/20mg contains torasemide which can increase the blood uric acid levels by increasing its absorption from the kidneys. Increased uric acid levels can cause a gout attack. Inform your doctor if you have hyperuricemia (excess of uric acid in blood) or a history of gout before taking this medicine. Use of Durite Plus 50mg/20mg should be avoided in patients with gout.
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Question
What is Durite Plus 50mg/20mg?
Durite Plus 50mg/20mg is a fixed-dose combination of torasemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body. The use of this combination is advised in patients of congestive heart failure (heart failure leading to fluid accumulation in the lung and rest of the body), nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (edema) and swelling of the abdomen (ascites).
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Question
What is the storage condition for the Durite Plus 50mg/20mg?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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Question
Is it safe to use Durite Plus 50mg/20mg?
Yes, Durite Plus 50mg/20mg is safe to use in most of the patients. However, in some patients it may cause common side effects like dizziness, dehydration, decreased sodium level in blood, breast enlargement in males, decreased magnesium level in blood, decreased calcium level in blood, increased blood uric acid. Inform your doctor if you experience any persistent problem while taking this medicine.
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Question
What are the contraindications to the use of Durite Plus 50mg/20mg?
The use of Durite Plus 50mg/20mg should be avoided in patients with hypersensitivity to torasemide, sulfonylureas or spironolactone or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs which cause renal damage, patients with high potassium levels (hyperkalemia), Addison's disease and in children with moderate to severe renal impairment.
Answer

Question
Can the use of Durite Plus 50mg/20mg cause hyperkalemia (increased potassium levels)?
Yes, Durite Plus 50mg/20mg can cause hyperkalemia (increased potassium levels). This occurs more commonly in patients with underlying kidney disease or in patients taking excessive potassium in their diet. High potassium levels can cause fatal heart problems. It is very important to get electrolytes and kidney function tests done on a regular basis while you are taking this medicine.
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Question
Can the use of Durite Plus 50mg/20mg cause dizziness?
Yes, the use of Durite Plus 50mg/20mg can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.
Answer
Question
What if you forget to take Durite Plus Tablet?
If you miss a dose of Durite Plus 50mg/20mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Durite Plus 50mg/20mg Tablet Reviews

Durite Plus 50mg/20mg is a combination of two medicines used to reduce excess fluid levels in the body while maintaining the potassium balance. It is used to treat edema (fluid overload) and some cases of hypertension.

It is best to take Durite Plus 50mg/20mg in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time everyday.  The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

Dehydration is very common side effect of this medicine. It might lower down the level of calcium, sodium, and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It might cause dizziness or tiredness, if happens rise slowly from sitting position or avoid driving.

Before taking this medicine, tell your doctor if you have any liver or kidney disease. Tell your doctor if you are pregnant or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

How Durite Plus 50mg/20mg Tablet Works

Durite Plus 50mg/20mg is a combination of two medicines: Spironolactone and Torasemide.

How to Use Durite Plus 50mg/20mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Durite Plus 50mg/20mg is to be taken with food.

Benefits of Durite Plus 50mg/20mg Tablet

  • In Treatment of Edema: Edema means swelling of the body due to excess water. Swelling usually occurs in the feet, legs, arms but it can involve your whole body. Durite Plus 50mg/20mg reduces swelling by increasing the amount of urine produced. This helps your body get rid of extra water and treats edema. Durite Plus 50mg/20mg helps maintain the level of potassium in the body. Altogether, this will help you go about your daily activities more easily and make you more confident about being active. Take it regularly and make appropriate lifestyle changes to help this medicine be more effective.

Uses of Durite Plus 50mg/20mg Tablet

  • Treatment of Edema

Durite Plus 50mg/20mg Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Durite Plus 50mg/20mg should be used with caution in patients with kidney disease. Dose adjustment of Durite Plus 50mg/20mg may be needed. Please consult your doctor.Use of Durite Plus 50mg/20mg is not recommended in patients with severe kidney disease.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Durite Plus 50mg/20mg.
Liver  CAUTION
Durite Plus 50mg/20mg should be used with caution in patients with liver disease. Dose adjustment of Durite Plus 50mg/20mg may be needed. Please consult your doctor.
Driving  UNSAFE
Durite Plus 50mg/20mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Pregnancy  CONSULT YOUR DOCTOR
Durite Plus 50mg/20mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding  SAFE IF PRESCRIBED
Durite Plus 50mg/20mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Quick Tips

  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • Durite Plus 50mg/20mg helps removes excess water from your body.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Your doctor may regularly monitor your blood pressure, kidney function and the level of salts such as potassium and sodium in your blood while you're taking this medication.
  • It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away.

References

  1. Torsemide and Spironolactone Tablets [Patient Information]. Ahmedabad, India: Torrent Pharmaceuticals Ltd.; 2015.
  2. Torsemide. Leganes Spain: Roche Farma S.A.; 2010.
  3. Drugs.com. Spironolactone Pregnancy and Breastfeeding Warnings.
  4. MedIndia. Spironolactone.

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