Epalpex 150 SR Tablet


Product Info

Prescription required Yes
Marketer Shilpex Pharmysis
Active Ingredient Epalrestat (150mg)
Storage Store below 30°C
Chemical ClassCarboxylic acid Derivative
Habit FormingNo
Therapeutic ClassANTI DIABETIC
Action ClassAldose reductase inhibitor
User Rating4.7
User Reviews378

FAQ

Question
What if you forget to take Epalpex Tablet SR?
If you miss a dose of Epalpex 150 SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Epalpex 150 SR Tablet Reviews

Epalpex 150 SR is used to treat diabetic nerve pain. Poorly controlled diabetes can eventually lead to diabetic nerve disease (neuropathy) as a complication. This medicine helps to relieve symptoms like burning pain and numbness seen in people with diabetic nerve disease.

Epalpex 150 SR belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly.  Do not stop taking it without asking your doctor, otherwise, your condition may worsen.

This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.

The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.

How Epalpex 150 SR Tablet Works

Epalpex 150 SR is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related to causing diabetic nerve disease.

How to Use Epalpex 150 SR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalpex 150 SR may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Epalpex 150 SR Tablet

  • In Diabetic nerve pain: High levels of blood sugar (glucose) levels in diabetic patients can cause damage to nerves and this can cause pain sensation. Epalpex 150 SR blocks the action of those chemicals that are responsible for causing pain sensation and even inflammation of the nerves due to diabetes. By relieving pain, it helps improve your quality of life. Keep taking it as advised by the doctor to get the most benefit.

Uses of Epalpex 150 SR Tablet

  • Diabetic nerve pain

Epalpex 150 SR Tablet Side Effects

Item form

Safety Tips

Liver  CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex 150 SR in patients with liver disease. Please consult your doctor.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Epalpex 150 SR.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Epalpex 150 SR during breastfeeding is not available. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Epalpex 150 SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney  CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex 150 SR in patients with kidney disease. Please consult your doctor.
Pregnancy  CONSULT YOUR DOCTOR
Information regarding the use of Epalpex 150 SR during pregnancy is not available. Please consult your doctor.

Quick Tips

  • If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.
  • If you have a foot injury or open wound, avoid engaging in weight-bearing activities.
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.

References

  1. Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44.
  2. MIMS, Malaysia. Epalrestat.
  3. Ramirez MA, Borja NL. Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008;28(5):646-55.

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