Epalrey-M Tablet


Product Info

Prescription required Yes
Marketer Sanrey Therapeutics
Active Ingredient Epalrestat (150mg) + Methylcobalamin (1500mcg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassANTI DIABETIC
User Rating4.4
User Reviews337

FAQ

Epalrey-M Tablet Reviews

Epalrey-M is a medicine used in the treatment of diabetic nerve disease. It protect the nerve fibers from damage and promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.

Epalrey-M may be taken with or without food, but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

The most common side effects of this medicine include nausea, vomiting, and increased liver enzymes. However, these are temporary and usually subside on their own. Please consult your doctor if these do not resolve or persist for a longer duration.

Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.

How Epalrey-M Tablet Works

Epalrey-M is a combination of two medicines:.

How to Use Epalrey-M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalrey-M may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Epalrey-M Tablet

  • In Diabetic nerve pain: Epalrey-M is a medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It interferes with pain signals that travel through the damaged nerves and the brain and also improves nerve conduction. Taking Epalrey-M regularly will improve your physical and social functioning and overall quality of life.

Uses of Epalrey-M Tablet

  • Diabetic nerve pain

Epalrey-M Tablet Side Effects

Item form

Safety Tips

Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Epalrey-M during breastfeeding is not available. Please consult your doctor.
Kidney  CONSULT YOUR DOCTOR
There is limited information available on the use of Epalrey-M in patients with kidney disease. Please consult your doctor.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Epalrey-M.
Liver  CONSULT YOUR DOCTOR
There is limited information available on the use of Epalrey-M in patients with liver disease. Please consult your doctor.
Pregnancy  CONSULT YOUR DOCTOR
Epalrey-M may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Epalrey-M alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Quick Tips

  • Inform your doctor if you have:Cut or sore on your feet that is infectious or not healingBurning or tingling sensation in arm or feet that hamper your routine activitiesTrouble in digestion, urination, or sexual functioningDizziness
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Dizziness
  • Take it only as per the dose and duration prescribed by your doctor. 
  • Trouble in digestion, urination, or sexual functioning
  • To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
  • Cut or sore on your feet that is infectious or not healing
  • Burning or tingling sensation in arm or feet that hamper your routine activities
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • Monitor your blood sugar level regularly.

References

  1. National Institues of Health. Vitamin B12.
  2. Sharma SR, Sharma N. Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective. Ann Indian Acad Neurol. 2008;11(4):231-35. [Accecssed 08 Apr. 2019] (online) Available from:
  3. Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44.

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