Eplemac 50mg Tablet


Product Info

Prescription required Yes
Marketer Innovative Pharmaceuticals
Active Ingredient Eplerenone (50mg)
Storage Store below 30°C
Chemical ClassPotassium sparing diuretics
Habit FormingNo
Therapeutic ClassCARDIAC
Action ClassPotassium- sparing Diuretics
User Rating4.3
User Reviews630

FAQ

Question
I had been using Losartan for quite some time and was tolerating it well. Now my doctor has prescribed me Eplemac 50mg along with Hydrochlorothiazide. I want to know why he just could not add Eplemac 50mg with Losartan?
It could be possible that Losartan was not able to control your blood pressure adequately. Therefore, your doctor may have suggested an alternative medicine for blood pressure control (Eplemac 50mg), but Eplerenone when taken with Losartan can enhance the chances of raised potassium levels which could be harmful for you. To prevent this rise in potassium levels, the combination of Eplemac 50mg with hydrochlorothiazide may have been prescribed.
Answer

Question
How long does Eplemac 50mg take to work?
Eplemac 50mg controls high blood pressure but does not cure it. You may not see any improvement because high blood pressure does not have any symptoms. But, if you get your blood pressure checked, you may notice a change within 2 weeks of starting Eplemac 50mg. However, the medicine may take 4 weeks or longer to show its maximum benefits.
Answer

Question
Does Eplemac 50mg cause erectile dysfunction?
No, Eplemac 50mg does not cause erectile dysfunction. Eplemac 50mg does not have any effect on fertility, in both males and females.
Answer

Question
What does Eplemac 50mg do? Is it a beta blocker or a diuretic?
Eplemac 50mg is a potassium-sparing diuretic. It is prescribed with other medicines to control increased blood pressure and to treat heart failure in patients who have had a heart attack. It is not a beta blocker but mineralocorticoid receptor blocker.
Answer

Question
Does Eplemac 50mg have any effect on the blood sugar levels?
Although it is not very common, but Eplemac 50mg may increase your blood sugar levels. Therefore, it is important that you keep a regular check on your blood sugar levels if you are a diabetic. The use of Eplemac 50mg should be avoided in patients who have type 2 diabetes along with some kidney problem in which the patient loses protein (albumin) in very small quantities in urine.
Answer

Question
Eplemac 50mg is a potassium-sparing diuretic. Does this mean that I will have more potassium in my body? Will it be beneficial for me?
Potassium-sparing diuretic are those medicines which increase the urination without causing any loss in potassium levels. Eplemac 50mg allows sodium loss by body in exchange for potassium which is retained. It may result in an increase in the levels of potassium. Therefore, your doctor may monitor your potassium levels continuously. You may need to get it measured before starting Eplemac 50mg, within the first week and one month after the start of treatment or after a change in dose. Potassium levels above normal range are not good for you or anyone.
Answer

Question
My blood pressure is now controlled, still the doctor has asked me to continue the treatment. Can I stop Eplemac 50mg?
No, you should not stop Eplemac 50mg. If your doctor has advised you to continue treatment, keep taking it. Eplemac 50mg does not cure blood pressure, but keeps the blood pressure in control. Therefore, keep taking the medicine even if your blood pressure is controlled. Stopping it may make your condition worse and you may have unwanted side effects.
Answer

Question
Is there anything I need to be careful about if I am taking aspirin and have now started Eplemac 50mg?
Aspirin may interfere with the working of Eplemac 50mg due to which your blood pressure may not get adequately controlled. Aspirin and Eplemac 50mg may increase the chances of rise in potassium levels in patients with kidney problems. Therefore, if both are to be used together, keep monitoring your blood pressure and potassium levels.
Answer
Question
What if you forget to take Eplemac Tablet?
If you miss a dose of Eplemac 50mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Answer

Eplemac 50mg Tablet Reviews

Eplemac 50mg is a medicine known as a diuretic (water pill). It is mainly used in the treatment of heart failure and high blood pressure. It is also used to reduce swelling (edema) caused by some other conditions.

Eplemac 50mg can be taken with or without food, but you should take it, in the same way, each time to get the most benefit. Taking it with food can reduce some side effects and taking it early in the day can prevent you from having to get up at night to go to the toilet. You should keep using this medicine as it has been prescribed, even if you feel well. If you stop taking it, your condition may get worse. If you are being treated for high blood pressure, lifestyle changes such as taking regular exercise and changes to your diet may increase the effectiveness of this medicine.

The common side effects include nausea, dizziness, diarrhea, headache, and cough. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Drinking alcohol can increase certain side effects.

You should be careful about using Eplemac 50mg if you have kidney problems or are unable to urinate. Before taking it, tell your doctor if you have ever had kidney, liver, or heart disease or you are pregnant. Also let your healthcare team know about all other medications you are using as they may affect, or be affected by this medicine. This medicine should only be used if it is clearly needed during pregnancy and while breastfeeding. While using this medicine, you may be advised to limit your intake of salt or salt substitutes, and you should have your blood pressure checked frequently. Some other tests will be done to monitor your progress.

How Eplemac 50mg Tablet Works

Eplemac 50mg is a potassium-sparing diuretic. It works by stopping aldosterone (a natural substance) from increasing your blood pressure. It also reduces the fluid around your heart. This helps improve your heart function after a heart attack and can help prevent heart attacks, strokes or heart failure getting worse.

How to Use Eplemac 50mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Eplemac 50mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Eplemac 50mg Tablet

  • In Treatment of Heart failure: Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Eplemac 50mg makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.
  • In Treatment of Hypertension (high blood pressure): Eplemac 50mg is generally used in combination with other medicines to control your blood pressure. It works by reducing the amount of water in the body by increasing the flow of urine. This way it lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.
  • In Treatment of Edema: Edema is caused by your body retaining too much water. Eplemac 50mg is a diuretic medicine (water pill) that helps get rid of the extra water and electrolytes from your body. It helps relieve symptoms such as swelling in your arms, legs, or abdomen. This will thus help you go about your daily activities more comfortably. Take it regularly and make appropriate lifestyle changes to get maximum benefits.

Uses of Eplemac 50mg Tablet

  • Treatment of Edema
  • Treatment of Hypertension (high blood pressure)
  • Treatment of Heart failure

Eplemac 50mg Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Eplemac 50mg should be used with caution in patients with kidney disease. Dose adjustment of Eplemac 50mg may be needed. Please consult your doctor.Use of Eplemac 50mg is not recommended in patients with severe kidney disease.
Driving  UNSAFE
Eplemac 50mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alcohol  UNSAFE
Eplemac 50mg may cause excessive drowsiness with alcohol.
Pregnancy  SAFE IF PRESCRIBED
Eplemac 50mg is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Liver  CAUTION
Eplemac 50mg should be used with caution in patients with liver disease. Dose adjustment of Eplemac 50mg may be needed. Please consult your doctor.Use of Eplemac 50mg is not recommended in patients with severe liver disease as the data available is limited.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Eplemac 50mg during breastfeeding is not available. Please consult your doctor.

Quick Tips

  • Your doctor will regularly check your kidney function and the amount of potassium in your blood while you are on this medicine.
  • Notify your doctor if you experience dizziness, diarrhea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing.
  • It can make you feel dizzy for the first few days. Do not drive or do anything requiring concentration until you know how Eplemac 50mg affects you.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Eplemac 50mg helps remove fluid from your body when used with other drugs.
  • It may increase the level of potassium in your blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.

References

  1. Hughes JC, Cassagnol M. Eplerenone. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.
  2. Eplerenone. New York, New York: Pfizer, Inc.; 2002 [revised May 2016].
  3. Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 159-61.
  4. Central Drugs Standard Control Organisation (CDSCO). Eplerenone.
  5. Eplerenone [Prescribing Information]. New York, NY: G.D. Searle LLC; 2021.
  6. Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 692-95.
  7. Eplerenone. West Ryde, New South Wales: Pfizer Australia Pty Ltd.; 2014.

Other Medical Preparations