Epnone 50 Tablet
Product Info
| Prescription required | Yes |
| Marketer | MSN Laboratories Ltd |
| Active Ingredient | Eplerenone (50mg) |
| Storage | Store below 30°C |
| Chemical Class | Potassium sparing diuretics |
| Habit Forming | No |
| Therapeutic Class | CARDIAC |
| Action Class | Potassium- sparing Diuretics |
| User Rating | 4.3 |
| User Reviews | 473 |
FAQ
My blood pressure is now controlled, still the doctor has asked me to continue the treatment. Can I stop Epnone 50?
No, you should not stop Epnone 50. If your doctor has advised you to continue treatment, keep taking it. Epnone 50 does not cure blood pressure, but keeps the blood pressure in control. Therefore, keep taking the medicine even if your blood pressure is controlled. Stopping it may make your condition worse and you may have unwanted side effects.
I had been using Losartan for quite some time and was tolerating it well. Now my doctor has prescribed me Epnone 50 along with Hydrochlorothiazide. I want to know why he just could not add Epnone 50 with Losartan?
It could be possible that Losartan was not able to control your blood pressure adequately. Therefore, your doctor may have suggested an alternative medicine for blood pressure control (Epnone 50), but Eplerenone when taken with Losartan can enhance the chances of raised potassium levels which could be harmful for you. To prevent this rise in potassium levels, the combination of Epnone 50 with hydrochlorothiazide may have been prescribed.
Is there anything I need to be careful about if I am taking aspirin and have now started Epnone 50?
Aspirin may interfere with the working of Epnone 50 due to which your blood pressure may not get adequately controlled. Aspirin and Epnone 50 may increase the chances of rise in potassium levels in patients with kidney problems. Therefore, if both are to be used together, keep monitoring your blood pressure and potassium levels.
Epnone 50 is a potassium-sparing diuretic. Does this mean that I will have more potassium in my body? Will it be beneficial for me?
Potassium-sparing diuretic are those medicines which increase the urination without causing any loss in potassium levels. Epnone 50 allows sodium loss by body in exchange for potassium which is retained. It may result in an increase in the levels of potassium. Therefore, your doctor may monitor your potassium levels continuously. You may need to get it measured before starting Epnone 50, within the first week and one month after the start of treatment or after a change in dose. Potassium levels above normal range are not good for you or anyone.
Does Epnone 50 cause erectile dysfunction?
No, Epnone 50 does not cause erectile dysfunction. Epnone 50 does not have any effect on fertility, in both males and females.
Does Epnone 50 have any effect on the blood sugar levels?
Although it is not very common, but Epnone 50 may increase your blood sugar levels. Therefore, it is important that you keep a regular check on your blood sugar levels if you are a diabetic. The use of Epnone 50 should be avoided in patients who have type 2 diabetes along with some kidney problem in which the patient loses protein (albumin) in very small quantities in urine.
How long does Epnone 50 take to work?
Epnone 50 controls high blood pressure but does not cure it. You may not see any improvement because high blood pressure does not have any symptoms. But, if you get your blood pressure checked, you may notice a change within 2 weeks of starting Epnone 50. However, the medicine may take 4 weeks or longer to show its maximum benefits.
What does Epnone 50 do? Is it a beta blocker or a diuretic?
Epnone 50 is a potassium-sparing diuretic. It is prescribed with other medicines to control increased blood pressure and to treat heart failure in patients who have had a heart attack. It is not a beta blocker but mineralocorticoid receptor blocker.
What if you forget to take Epnone Tablet?
If you miss a dose of Epnone 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Epnone 50 Tablet Reviews
Epnone 50 is a medicine known as a diuretic (water pill). It is mainly used in the treatment of heart failure and high blood pressure. It is also used to reduce swelling (edema) caused by some other conditions.
Epnone 50 can be taken with or without food, but you should take it, in the same way, each time to get the most benefit. Taking it with food can reduce some side effects and taking it early in the day can prevent you from having to get up at night to go to the toilet. You should keep using this medicine as it has been prescribed, even if you feel well. If you stop taking it, your condition may get worse. If you are being treated for high blood pressure, lifestyle changes such as taking regular exercise and changes to your diet may increase the effectiveness of this medicine.
The common side effects include nausea, dizziness, diarrhea, headache, and cough. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Drinking alcohol can increase certain side effects.
You should be careful about using Epnone 50 if you have kidney problems or are unable to urinate. Before taking it, tell your doctor if you have ever had kidney, liver, or heart disease or you are pregnant. Also let your healthcare team know about all other medications you are using as they may affect, or be affected by this medicine. This medicine should only be used if it is clearly needed during pregnancy and while breastfeeding. While using this medicine, you may be advised to limit your intake of salt or salt substitutes, and you should have your blood pressure checked frequently. Some other tests will be done to monitor your progress.
Epnone 50 can be taken with or without food, but you should take it, in the same way, each time to get the most benefit. Taking it with food can reduce some side effects and taking it early in the day can prevent you from having to get up at night to go to the toilet. You should keep using this medicine as it has been prescribed, even if you feel well. If you stop taking it, your condition may get worse. If you are being treated for high blood pressure, lifestyle changes such as taking regular exercise and changes to your diet may increase the effectiveness of this medicine.
The common side effects include nausea, dizziness, diarrhea, headache, and cough. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Drinking alcohol can increase certain side effects.
You should be careful about using Epnone 50 if you have kidney problems or are unable to urinate. Before taking it, tell your doctor if you have ever had kidney, liver, or heart disease or you are pregnant. Also let your healthcare team know about all other medications you are using as they may affect, or be affected by this medicine. This medicine should only be used if it is clearly needed during pregnancy and while breastfeeding. While using this medicine, you may be advised to limit your intake of salt or salt substitutes, and you should have your blood pressure checked frequently. Some other tests will be done to monitor your progress.
How Epnone 50 Tablet Works
Epnone 50 is a potassium-sparing diuretic. It works by stopping aldosterone (a natural substance) from increasing your blood pressure. It also reduces the fluid around your heart. This helps improve your heart function after a heart attack and can help prevent heart attacks, strokes or heart failure getting worse.
How to Use Epnone 50 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epnone 50 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Epnone 50 Tablet
- In Treatment of Heart failure: Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Epnone 50 makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.
- In Treatment of Hypertension (high blood pressure): Epnone 50 is generally used in combination with other medicines to control your blood pressure. It works by reducing the amount of water in the body by increasing the flow of urine. This way it lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.
- In Treatment of Edema: Edema is caused by your body retaining too much water. Epnone 50 is a diuretic medicine (water pill) that helps get rid of the extra water and electrolytes from your body. It helps relieve symptoms such as swelling in your arms, legs, or abdomen. This will thus help you go about your daily activities more comfortably. Take it regularly and make appropriate lifestyle changes to get maximum benefits.
Uses of Epnone 50 Tablet
- Treatment of Heart failure
- Treatment of Hypertension (high blood pressure)
- Treatment of Edema
Epnone 50 Tablet Side Effects
Safety Tips
Alcohol
UNSAFE
Epnone 50 may cause excessive drowsiness with alcohol.
Liver
CAUTION
Epnone 50 should be used with caution in patients with liver disease. Dose adjustment of Epnone 50 may be needed. Please consult your doctor.Use of Epnone 50 is not recommended in patients with severe liver disease as the data available is limited.
Pregnancy
SAFE IF PRESCRIBED
Epnone 50 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Kidney
CAUTION
Epnone 50 should be used with caution in patients with kidney disease. Dose adjustment of Epnone 50 may be needed. Please consult your doctor.Use of Epnone 50 is not recommended in patients with severe kidney disease.
Driving
UNSAFE
Epnone 50 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Epnone 50 during breastfeeding is not available. Please consult your doctor.
Quick Tips
- Your doctor will regularly check your kidney function and the amount of potassium in your blood while you are on this medicine.
- Notify your doctor if you experience dizziness, diarrhea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing.
- It can make you feel dizzy for the first few days. Do not drive or do anything requiring concentration until you know how Epnone 50 affects you.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- It may increase the level of potassium in your blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
- Epnone 50 helps remove fluid from your body when used with other drugs.
References
- Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 692-95.
- Eplerenone. West Ryde, New South Wales: Pfizer Australia Pty Ltd.; 2014.
- Central Drugs Standard Control Organisation (CDSCO). Eplerenone.
- Eplerenone. New York, New York: Pfizer, Inc.; 2002 [revised May 2016].
- Hughes JC, Cassagnol M. Eplerenone. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.
- Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 159-61.
- Eplerenone [Prescribing Information]. New York, NY: G.D. Searle LLC; 2021.