Glibedac PM 5mg/500mg/15mg Tablet


Product Info

Prescription required Yes
Marketer Innovative Pharmaceuticals
Active Ingredient Glibenclamide (5mg) + Metformin (500mg) + Pioglitazone (15mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassANTI DIABETIC
User Rating4.4
User Reviews754

FAQ

Question
What if you forget to take Glibedac PM Tablet?
If you miss a dose of Glibedac PM 5mg/500mg/15mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Glibedac PM 5mg/500mg/15mg Tablet Reviews

Glibedac PM 5mg/500mg/15mg belongs to a category of medicines known as anti-diabetic drugs. It is a combination of medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glibedac PM 5mg/500mg/15mg should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Glibedac PM 5mg/500mg/15mg is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

How Glibedac PM 5mg/500mg/15mg Tablet Works

Glibedac PM 5mg/500mg/15mg is a combination of three antidiabetic medicines: Glibenclamide, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

How to Use Glibedac PM 5mg/500mg/15mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glibedac PM 5mg/500mg/15mg is to be taken with food.

Benefits of Glibedac PM 5mg/500mg/15mg Tablet

  • In Treatment of Type 2 diabetes mellitus: Glibedac PM 5mg/500mg/15mg is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Uses of Glibedac PM 5mg/500mg/15mg Tablet

  • Treatment of Type 2 diabetes mellitus

Glibedac PM 5mg/500mg/15mg Tablet Side Effects

Item form

Safety Tips

Liver  CAUTION
Glibedac PM 5mg/500mg/15mg should be used with caution in patients with liver disease. Dose adjustment of Glibedac PM 5mg/500mg/15mg may be needed. Please consult your doctor.Use of Glibedac PM 5mg/500mg/15mg is not recommended in patients with severe liver disease.
Kidney  UNSAFE
Glibedac PM 5mg/500mg/15mg is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Glibedac PM 5mg/500mg/15mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Glibedac PM 5mg/500mg/15mg.
Pregnancy  CONSULT YOUR DOCTOR
Glibedac PM 5mg/500mg/15mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding  UNSAFE
Glibedac PM 5mg/500mg/15mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Quick Tips

  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
  • Take it with food to lower your chance of having an upset stomach.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

References

  1. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003.
  2. Glibenclamide, Pioglitazone and Metformin Hydrochloride (SR) [Product Description]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2014.
  3. Panikar V, Chandalia HB, Joshi SR, et al. Beneficial effects of triple drug combination of pioglitazone with glibenclamide and metformin in type 2 diabetes mellitus patients on insulin therapy. J Assoc Physicians India. 2003;51:1061-4.
  4. Glibenclamide+Pioglitazone+Metformin hydrochloride tablets [Prescribing Information]. Sikkim, India. Torrent Pharmaceuticals Ltd.; 2020.

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