Glucobay M50 Tablet


Product Info

Prescription required Yes
Marketer Bayer Zydus Pharma Pvt Ltd
Active Ingredient Acarbose (50mg) + Metformin (500mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassANTI DIABETIC
User Rating4.3
User Reviews664

FAQ

Question
What if you forget to take Glucobay M Tablet?
If you miss a dose of Glucobay M50, skip it and continue with your normal schedule. Do not double the dose.
Answer

Glucobay M50 Tablet Reviews

Glucobay M50 is an anti-diabetic drug used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glucobay M50 should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you, and this may change from time to time according to how it is working as per your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Along with taking this medicine, you should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of this medicine may include flatulence, diarrhea, abdominal pain, fluid retention (edema), and increased liver enzymes. However, these are temporary and usually subside on their own. If these do not resolve or worry you, please consult your doctor. He/she might suggest ways of dealing with your side effects or treating them if they are bothersome.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may advise blood tests to monitor your blood cell counts and liver function.

How Glucobay M50 Tablet Works

Glucobay M50 is a combination of two antidiabetic medicines:.

How to Use Glucobay M50 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glucobay M50 is to be taken with food.

Benefits of Glucobay M50 Tablet

  • In Treatment of Type 2 diabetes mellitus: Glucobay M50 is a medicine that helps to control high blood glucose (sugar) levels when given in combination with other anti-diabetics. It works by slowing down the digestion and absorption of glucose (carbohydrates) from your digestive tract, thereby decreasing the rise in blood glucose levels after meals. It also helps get rid of extra glucose from your body through urine.Lowering blood glucose levels is an essential part of managing diabetes and reduces the risk of getting serious complications of diabetes such as kidney or eye damage, nerve problems and loss of limbs.This medicine will also reduce the risk of death from cardiovascular disease if you have type 2 diabetes and already have cardiovascular disease. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Uses of Glucobay M50 Tablet

  • Treatment of Type 2 diabetes mellitus

Glucobay M50 Tablet Side Effects

Item form

Safety Tips

Liver  UNSAFE
Glucobay M50 is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Kidney  SAFE IF PRESCRIBED
Glucobay M50 is safe to use in patients with kidney disease. No dose adjustment of Glucobay M50 is recommended.Use of Glucobay M50 is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Pregnancy  CONSULT YOUR DOCTOR
Glucobay M50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding  CAUTION
Glucobay M50 should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving  CONSULT YOUR DOCTOR
It is not known whether Glucobay M50 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Glucobay M50.

Quick Tips

  • Your doctor will also advise you to test for sugar in your blood using a home diabetes test kit regularly to check that your sugar level is being controlled.
  • Along with a healthy diet, indulge in light exercises regularly and quit smoking and drinking.
  • Seek immediate medical help if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as Glucobay M50 may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Hypoglycemia (low blood sugar level) may occur if Glucobay M50 is taken along with other antidiabetic medicines, alcohol, or on delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief.
  • Along with your regular doctor visit, you might also need regular check-ups with an eye clinic and a foot clinic as well.
  • If you feel excessively thirsty, pass urine more frequently, and get tired easily, then let your doctor know. These are the signs of very high sugar levels in your blood and your treatment may need adjusting.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as Glucobay M50 may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

References

  1. Acarbose [Product Monograph]. Ottawa, ON: Marcan Pharmaceuticals Inc.; 2019.
  2. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company.
  3. Joshi SR, Ramachandran A, Chadha M, et al. Acarbose plus metformin fixed-dose combination in the management of type 2 diabetes. Expert Opin Pharmacother. 2014;15(11):1611-20.
  4. Liu Z, Zhao X, Sun W, et al. Metformin combined with acarbose vs. single medicine in the treatment of type 2 diabetes: A meta-analysis. Exp Ther Med. 2017;13(6):3137-3145.
  5. Diabetes UK. Glucobay (Acarbose).
  6. Metformin hydrochloride [Product Label]. Princeton, NJ: Bristol-Myers Squibb Company.
  7. Diabetes Community, UK. Glucobay (Acarbose).
  8. Salemi Z, Rafie E, Goodarzi M T. Effect of Metformin, Acarbose and Their Combination on the Serum Visfatin Level in Nicotinamide/Streptozocin-Induced Type 2 Diabetic Rats. Iran Red Crescent Med J. 2016;18(3):e23814.
  9. Metformin hydrochloride. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 8 Apr. 2017]

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