Glyfine M 80mg/500mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Lifecom Pharmaceuticals Pvt Ltd
Active Ingredient	Gliclazide (80mg) + Metformin (500mg)
Storage	Store below 30°C
Habit Forming	No
Therapeutic Class	ANTI DIABETIC
User Rating	4.5
User Reviews	340

FAQ

Is it safe to take alcohol while I am also taking Glyfine M 80mg/500mg?

No, it is not safe to take alcohol along with Glyfine M 80mg/500mg. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Can the use of Glyfine M 80mg/500mg cause lactic acidosis?

Yes, the use of Glyfine M 80mg/500mg can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glyfine M 80mg/500mg and immediately consult your doctor.

What is Glyfine M 80mg/500mg?

Glyfine M 80mg/500mg is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Are there any specific conditions in which Glyfine M 80mg/500mg should not to be taken?

The use of Glyfine M 80mg/500mg should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Are there any specific conditions in which Glyfine M 80mg/500mg should not to be taken?

Is it safe to take alcohol while I am also taking Glyfine M 80mg/500mg?

No, it is not safe to take alcohol along with Glyfine M 80mg/500mg. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

What are the possible side effects of Glyfine M 80mg/500mg?

The use of Glyfine M 80mg/500mg is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Glyfine M 80mg/500mg cause lactic acidosis?

Can the use of Glyfine M 80mg/500mg cause hypoglycemia?

Yes, the use of Glyfine M 80mg/500mg can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

What are the possible side effects of Glyfine M 80mg/500mg?

Can the use of Glyfine M 80mg/500mg lead to Vitamin B12 deficiency?

Yes, the use of Glyfine M 80mg/500mg can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Can the use of Glyfine M 80mg/500mg lead to Vitamin B12 deficiency?

What is Glyfine M 80mg/500mg?

Can the use of Glyfine M 80mg/500mg cause hypoglycemia?

What if you forget to take Glyfine M Tablet?

If you miss a dose of Glyfine M 80mg/500mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Glyfine M 80mg/500mg Tablet Reviews

Glyfine M 80mg/500mg belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glyfine M 80mg/500mg should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Glyfine M 80mg/500mg are low blood glucose levels (hypoglycemia), constipation, and vomiting. Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

How Glyfine M 80mg/500mg Tablet Works

Glyfine M 80mg/500mg is a combination of two antidiabetic medicines: Gliclazide and Metformin.

How to Use Glyfine M 80mg/500mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyfine M 80mg/500mg is to be taken with food.

Uses of Glyfine M 80mg/500mg Tablet

Type 2 diabetes mellitus

Glyfine M 80mg/500mg Tablet Side Effects

Safety Tips

Driving ^CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Liver ^CAUTION

Glyfine M 80mg/500mg should be used with caution in patients with liver disease. Dose adjustment of Glyfine M 80mg/500mg may be needed. Please consult your doctor.Glyfine M 80mg/500mg is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Breast feeding ^{CONSULT YOUR DOCTOR}

Glyfine M 80mg/500mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Pregnancy ^{CONSULT YOUR DOCTOR}

Glyfine M 80mg/500mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Kidney ^CAUTION

Glyfine M 80mg/500mg should be used with caution in patients with kidney disease. Dose adjustment of Glyfine M 80mg/500mg may be needed. Please consult your doctor.Use of Glyfine M 80mg/500mg is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Alcohol ^UNSAFE

It is unsafe to consume alcohol with Glyfine M 80mg/500mg.

Quick Tips

Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyfine M 80mg/500mg may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyfine M 80mg/500mg may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Monitor your blood sugar level regularly while you are taking this medicine.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.