Glyphase M3 Forte Tablet PR


Product Info

Prescription required Yes
Marketer Griffins Life Sciences Pvt. Ltd
Active Ingredient Glimepiride (3mg) + Metformin (1000mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassANTI DIABETIC
User Rating4.4
User Reviews574

FAQ

Question
Is it safe to take alcohol while I am also taking Glyphase M3 Forte?
No, it is not safe to take Glyphase M3 Forte along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.
Answer

Question
Can the use of Glyphase M3 Forte lead to Vitamin B12 deficiency?
Yes, the use of Glyphase M3 Forte can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
Answer

Question
What is Glyphase M3 Forte?
Glyphase M3 Forte is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
Answer

Question
Can the use of Glyphase M3 Forte lead to lactic acidosis?
Yes, the use of Glyphase M3 Forte can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glyphase M3 Forte and consult your doctor immediately.
Answer

Question
What are the possible side effects of Glyphase M3 Forte?
The use of Glyphase M3 Forte is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
Answer

Question
Can the use of Glyphase M3 Forte cause hypoglycemia?
Yes, the use of Glyphase M3 Forte can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.
Answer

Question
What are the recommended storage conditions for Glyphase M3 Forte?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Answer
Question
What if you forget to take Glyphase M Tablet PR?
If you miss a dose of Glyphase M3 Forte, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Glyphase M3 Forte Tablet PR Reviews

Glyphase M3 Forte belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glyphase M3 Forte should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Glyphase M3 Forte is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

How Glyphase M3 Forte Tablet PR Works

Glyphase M3 Forte is a combination of two antidiabetic medicines: Glimepiride and Metformin.Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

How to Use Glyphase M3 Forte Tablet PR

Use it as advised by your doctor or check the label for directions before use. Glyphase M3 Forte is to be taken with food.

Benefits of Glyphase M3 Forte Tablet PR

  • In Treatment of Type 2 diabetes mellitus: Glyphase M3 Forte is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Uses of Glyphase M3 Forte Tablet PR

  • Treatment of Type 2 diabetes mellitus

Glyphase M3 Forte Tablet PR Side Effects

Item form

Safety Tips

Alcohol  UNSAFE
It is unsafe to consume alcohol with Glyphase M3 Forte.
Pregnancy  CONSULT YOUR DOCTOR
Glyphase M3 Forte may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding  UNSAFE
Glyphase M3 Forte is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Kidney  CAUTION
Glyphase M3 Forte should be used with caution in patients with kidney disease. Dose adjustment of Glyphase M3 Forte may be needed. Please consult your doctor.Use of Glyphase M3 Forte is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Driving  CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Liver  CAUTION
Glyphase M3 Forte should be used with caution in patients with liver disease. Dose adjustment of Glyphase M3 Forte may be needed. Please consult your doctor.Glyphase M3 Forte is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Quick Tips

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Glyphase M3 Forte.
  • Take it with food to lower your chance of having an upset stomach.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyphase M3 Forte may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

References

  1. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009.
  2. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company.
  3. American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110.
  4. Glimepiride and Metformin Hydrochloride Sustained Release [Patient Information Sheet]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2016.

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