Imutaj 10mg Tablet


Product Info

Prescription required Yes
Marketer Taj Pharma India Ltd
Active Ingredient Methotrexate (10mg)
Storage Store below 30°C
Chemical ClassGlutamic Acid Derivative
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolite- Methotrexate
User Rating4.5
User Reviews653

FAQ

Question
Can Imutaj 10mg use make me more prone to infections?
Imutaj 10mg may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Imutaj 10mg use. If you have an active infection, Imutaj 10mg should be used with extreme caution.
Answer

Question
Why do I have to take folic acid with Imutaj 10mg?
Folic acid is required to make new cells in the body and Imutaj 10mg decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Imutaj 10mg such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.
Answer

Question
Why do I need to take regular blood tests while taking Imutaj 10mg?
Regular blood tests will help your doctor to check your response to Imutaj 10mg and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.
Answer

Question
Can Imutaj 10mg cause mouth ulcers?
Yes, Imutaj 10mg can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.
Answer

Question
What to do if I am planning to become pregnant and my husband is taking Imutaj 10mg?
You should avoid pregnancy if your husband is taking Imutaj 10mg. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.
Answer

Question
Can Imutaj 10mg affect fertility?
Yes, Imutaj 10mg may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.
Answer
Question
What if you forget to take Imutaj Tablet?
If you miss a dose of Imutaj 10mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Imutaj 10mg Tablet Reviews

Imutaj 10mg is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.

Imutaj 10mg may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage.

The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.

Before taking it, tell your doctor if you have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.

How Imutaj 10mg Tablet Works

Imutaj 10mg inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Imutaj 10mg kills cancer cells by preventing them from making DNA. Imutaj 10mg can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Imutaj 10mg may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis, or damage to bowel in Crohn's disease.

How to Use Imutaj 10mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Imutaj 10mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Imutaj 10mg Tablet

  • In Treatment of Psoriasis: Imutaj 10mg belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Imutaj 10mg works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
  • In Treatment of Cancer: Imutaj 10mg works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
  • In Treatment of Crohn’s disease: Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Imutaj 10mg helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.
  • In Treatment of Rheumatoid arthritis: Imutaj 10mg belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body's immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective.

Uses of Imutaj 10mg Tablet

  • Treatment of Crohn’s disease
  • Treatment of Cancer
  • Treatment of Rheumatoid arthritis
  • Treatment of Psoriasis

Imutaj 10mg Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Imutaj 10mg should be used with caution in patients with kidney disease. Dose adjustment of Imutaj 10mg may be needed. Please consult your doctor.Regular monitoring of kidney function test is advised while you are taking this medicine.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Imutaj 10mg.
Pregnancy  UNSAFE
Imutaj 10mg is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Driving  UNSAFE
Imutaj 10mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Breast feeding  UNSAFE
Imutaj 10mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Liver  CAUTION
Imutaj 10mg should be used with caution in patients with liver disease. Dose adjustment of Imutaj 10mg may be needed. Please consult your doctor.

Quick Tips

  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
  • It may take from weeks to months for Imutaj 10mg to work. Keep taking the medication as prescribed.
  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine.

References

  1. Crohn's & Colitis, UK. Methotrexate [Information Sheet].
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022
  4. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  5. Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020.
  6. Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022.
  7. CiplaMed. Methotrexate [Prescribing Information]. [Last Reviewed: Feb 2019].
  8. Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022].

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