Jastinib Tablet
Product Info
| Prescription required | Yes |
| Marketer | Jasgur Life Sciences |
| Active Ingredient | Axitinib (5mg) |
| Storage | Store below 30°C |
| Chemical Class | Enzamide and Indazole Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| User Rating | 4.8 |
| User Reviews | 655 |
FAQ
Does Jastinib affect fertility?
Yes, this medicine may cause fertility issues in males as well as females. Talk to your doctor before starting your treatment to know about ways to preserve fertility.
I feel exhausted after starting treatment with Jastinib. What should I do?
General tiredness/fatigue is a common side effect experienced during treatment with Jastinib. You may need to adjust your schedule to manage fatigue. Take ample amounts of rest and do not indulge in physically exhausting activities. Exercise, such as walking, can help cope up with fatigue.
What are the possible signs and symptoms of kidney cancer?
Some possible signs and symptoms of kidney cancer include blood in the urine (hematuria) which may appear dark red, orange, or pink. As kidney cancer progresses, it may produce other symptoms such as persistent pain, pressure just below the ribs, or intense fatigue.
I have swelling in my ankles and feet after I started taking Jastinibs? What does this mean?
This medicine may cause side effects such as excessive tiredness, swelling of the abdomen, legs, or ankles, shortness of breath, or protruding neck veins. These are alarming and indicate chances of developing heart failure. The use of Jastinib is associated with an increased risk of heart failure events and these symptoms must therefore be taken seriously and addressed at the earliest. Tell your doctor without any delay if you notice any of these episodes.
When should I call my doctor right away?
Get medical help right away if you have signs of allergic reaction such as rash, hives, itching, and blisters. Also, let your doctor know if you notice bleeding or blood in your cough, very high blood pressure, signs of thyroid problems such as a change in weight, nervousness, restlessness, weakness, thinning of hair after taking Jastinib. Also, if you feel sudden mood changes, fast heart rate, change in voice, fever, or chills, visit your doctor without delay.
What lab tests are important before starting Jastinib?
Your doctor may advise you to undergo lab or medical tests such as blood pressure, thyroid function, kidney function, liver or pancreatic function tests, complete blood counts, urine tests, blood mineral levels including sodium or potassium before starting this medication. Women of childbearing age should have a pregnancy test before starting this medicine.
Who should not take the Jastinib?
People who are allergic to axitinib or any other ingredient of this medicine should not take Jastinib. Talk to your doctor if you are not sure.
What is Reversible Posterior Leukoencephalopathy Syndrome?
Reversible Posterior Leukoencephalopathy Syndrome (RPLS) is a rare but serious neurological complication associated with the use of Jastinib. It is characterized by symptoms such as headaches, vision problems, mental changes, seizures, high blood pressure, weakness, and swelling in the brain. This condition is reversible and symptoms subsides once treated. Consult your doctor right away if you experience any of these worrisome episodes while taking Inlyta tablets.
How do I know if I have developed thyroid problems after taking Jastinib?
Regular monitoring of thyroid function is recommended before as well as during your treatment with Jastinib. Your doctor will advise blood tests to assess the same. Tell your doctor if you have symptoms such as feeling more tired than usual, weight gain or loss, sensitivity to hot or cold weather, hair loss, voice changes (such as deepening of the voice), muscle cramps, and aches.
How long should I take the Jastinib?
The duration of treatment varies from person to person. Your doctor will decide treatment duration based on your condition, response to treatment, and tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience side effects.
How can I store Jastinib at home?
Store the medicine at room temperature at a dry place beyond the reach of the children and pets to avoid any accidental intake.
Jastinib Tablet Reviews
Jastinib is an anti-cancer medicine used in the treatment of kidney cancer.
Jastinib can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include high blood pressure, joint pain, and loss of appetite. Diarrhea, shortness of breath, can be serious sometimes so take medicine to treat it as prescribed by the doctor or stay hydrated. Your doctor may advise for regular blood pressure checkups while you are taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea or vomiting.
Before taking it, tell your doctor if you have thyroid problems, liver or bleeding problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by females during treatment is important to avoid pregnancy.
Jastinib can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include high blood pressure, joint pain, and loss of appetite. Diarrhea, shortness of breath, can be serious sometimes so take medicine to treat it as prescribed by the doctor or stay hydrated. Your doctor may advise for regular blood pressure checkups while you are taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea or vomiting.
Before taking it, tell your doctor if you have thyroid problems, liver or bleeding problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by females during treatment is important to avoid pregnancy.
How Jastinib Tablet Works
Jastinib is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
How to Use Jastinib Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jastinib may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Jastinib Tablet
- In Kidney cancer: Jastinib is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.
Uses of Jastinib Tablet
- Kidney cancer
Jastinib Tablet Side Effects
- Vomiting
- Abdominal pain
- Indigestion
- Stomatitis (Inflammation of the mouth)
- Loss of appetite
- Breathlessness
- Dry skin
- Painful blisters on hands and feet
- Diarrhea
- Cough
- Constipation
- Nausea
- Difficulty in speaking
- Taste change
- Breathing problems
- Headache
- High blood pressure
- Decreased level of thyroid hormones
- Decreased appetite
- Pain in extremities
- Rash
- Protein in urine
- Joint pain
Safety Tips
Driving
UNSAFE
Jastinib may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Jastinib. Please consult your doctor.
Liver
CAUTION
Jastinib should be used with caution in patients with liver disease. Dose adjustment of Jastinib may be needed. Please consult your doctor.Limited information is available on the use of Jastinib in patients with the severe liver disease.
Kidney
SAFE IF PRESCRIBED
Jastinib is safe to use in patients with kidney disease. No dose adjustment of Jastinib is recommended.
Breast feeding
CONSULT YOUR DOCTOR
Jastinib is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy
CONSULT YOUR DOCTOR
Jastinib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Quick Tips
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Take it with or without food, preferably at the same time each day.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 111-12.
- Axitinib. Sandwich, Kent: Pfizer Limited; 2012 [revised Nov. 2018].
- Central Drugs Standard Control Organisation (CDSCO).
- Axitinib. New York, New York: Pfizer Inc.; 2012 [revised Aug. 2014].