Larentine 5 Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	La Renon Healthcare Pvt Ltd
Active Ingredient	Memantine (5mg)
Storage	Store below 30°C
Chemical Class	Amantadine Derivative
Habit Forming	No
Therapeutic Class	NEURO CNS
Action Class	NMDA inhibitors- Alzheimer's disease
User Rating	4.4
User Reviews	536

FAQ

Does Larentine 5 make you sleepy?

Yes, Larentine 5 may make you sleepy. Larentine 5 has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.

Can I stop taking Larentine 5 if I feel better?

No, keep using Larentine 5 as advised by your doctor, even if you feel well. Stopping Larentine 5 can bring back your symptoms of dementia.

Does Larentine 5 have any interaction with cardiac medicines?

Yes, Larentine 5 may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Larentine 5 which may cause increased toxicity.

Does Larentine 5 have abuse potential?

No, Larentine 5 does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.

When and how Larentine 5 should be taken?

Larentine 5 should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.

How does Larentine 5 affect a person with dementia?

Larentine 5 belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Larentine 5 may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.

Can Larentine 5 be combined with donepezil?

Yes, Larentine 5 can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.

What are the symptoms of overdosage of Larentine 5?

The symptoms which can be observed due to an overdose of Larentine 5 include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.

What is dementia?

Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.

How long does it take for Larentine 5 to start working?

For Larentine 5 to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.

Can I just stop taking Larentine 5?

No, Larentine 5 should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.

What medicines should I avoid while taking Larentine 5?

Larentine 5 can interact with several medicines. Taking other medicines along with Larentine 5 can either make Larentine 5 less effective or increase its side effect. Do not take any medicine without talking to your doctor.

What if you forget to take Larentine Tablet?

If you miss a dose of Larentine 5, skip it and continue with your normal schedule. Do not double the dose.

Larentine 5 Tablet Reviews

Larentine 5 is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.

Larentine 5 maybe taken with or without food. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. If you missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.

The most common side effects of this medicine are dizziness, headache, confusion, and constipation. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking this medicine, inform the doctor if you have a history of seizures, kidney disease, heart disease, or liver disease. Let your doctor also know if you are taking any other medicines for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.

How Larentine 5 Tablet Works

Larentine 5 is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Larentine 5 works by preventing the action of NMDA receptors and regulates the production of glutamate. involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.

How to Use Larentine 5 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larentine 5 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Larentine 5 Tablet

In Alzheimer's disease: Larentine 5 improves learning, memory and information processing (cognitive function) in people with moderate to severe Alzheimer's disease. These problems in memory and thinking may start interfering with daily activities and worsen your condition. This medicine will help in managing Alzheimer’s disease effectively. It will make it easier for you to carry out your daily activities and improve your quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve; so keep using the medicine even if you do not think it is working.

Uses of Larentine 5 Tablet

Alzheimer's disease

Larentine 5 Tablet Side Effects

Safety Tips

Breast feeding ^{CONSULT YOUR DOCTOR}

Information regarding the use of Larentine 5 during breastfeeding is not available. Please consult your doctor.

Driving ^UNSAFE

Larentine 5 may cause side effects which could affect your ability to drive.

Liver ^CAUTION

Larentine 5 should be used with caution in patients with severe liver disease. Dose adjustment of Larentine 5 may be needed. Please consult your doctor.Limited information is available on the use of Larentine 5 in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Pregnancy ^{SAFE IF PRESCRIBED}

Larentine 5 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Alcohol ^CAUTION

Caution is advised when consuming alcohol with Larentine 5. Please consult your doctor.

Kidney ^CAUTION

Larentine 5 should be used with caution in patients with severe kidney disease. Dose adjustment of Larentine 5 may be needed. Please consult your doctor.

Quick Tips

It is well tolerated and has lesser side effects as compared to other similar medicines.
Be cautious while driving or doing anything that requires concentration until you know how Larentine 5 affects you.
Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
You have been prescribed Larentine 5 to treat dementia (memory loss) in patients with Alzheimer's disease.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

References

Memantine HCl. Dublin, Ireland: Forest Laboratories Ireland Ltd.; 2003 [revised Oct 2013].
Memantine hydrochloride [EMC SmPC]. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2013 [revised Jun. 2015].
Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
Memantine hydrochloride [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited (Formulation Division); 2023.
Central Drugs Standard Control Organisation. Memantine.
Memantine Hydrochloride [Patient Information Leaflet]. Bachupally, India: Dr. Reddy’s Laboratories Limited.
Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
Central Drugs Standard Control Organisation (CDSCO).
Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.