Lefron 20mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Dermajoint India
Active Ingredient	Leflunomide (20mg)
Storage	Store below 30°C
Chemical Class	Isoxazole Derivative
Habit Forming	No
Therapeutic Class	PAIN ANALGESICS
Action Class	Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics
User Rating	4.3
User Reviews	631

FAQ

Can Lefron 20mg cause cancer?

Lefron 20mg may increase your chances of cancer especially of lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Lefron 20mg. Discuss with your doctor if you have concerns regarding it.

Can I plan pregnancy after stopping Lefron 20mg?

Lefron 20mg takes fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Lefron 20mg. This extensive time duration may be reduced to a few weeks by taking certain medicines which can help speed up the removal of Lefron 20mg from your body.

How long does it take to see improvement after starting Lefron 20mg?

Lefron 20mg may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor who will analyze the condition.

When should patients notify their doctor?

The doctor should be informed if one has lung problems like cough, shortness of breath or if one observes symptoms of infection like fever, weakens, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives rashes and liver problems like yellowing of skin, loss of appetite then it should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.

Can Lefron 20mg cause weight loss?

Yes, Lefron 20mg may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this reduction in weight could be due to accompanying loss of appetite. Consult your doctor if your weight loss is significant.

What if you forget to take Lefron Tablet?

If you miss a dose of Lefron 20mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Lefron 20mg Tablet Reviews

Lefron 20mg is used in the treatment of rheumatoid arthritis and psoriatic arthritis. It helps in slowing down the progression of the disease and provide relief from pain, swelling, and redness.

Lefron 20mg can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.

Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor of all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or effecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

How Lefron 20mg Tablet Works

Lefron 20mg blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain autoimmune diseases. It suppresses the underlying disease process, rather than simply treating the disease.

How to Use Lefron 20mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefron 20mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Lefron 20mg Tablet

In Rheumatoid arthritis: Lefron 20mg reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.
In Psoriatic arthritis: Psoriatic arthritis is a form of arthritis that affects some people who have psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. Psoriatic arthritis is a type of inflammatory arthritis. Symptoms include joint pain, stiffness and swelling, which may flare and subside. Lefron 20mg helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

Uses of Lefron 20mg Tablet

Psoriatic arthritis
Rheumatoid arthritis

Lefron 20mg Tablet Side Effects

Safety Tips

Alcohol ^UNSAFE

It is unsafe to consume alcohol with Lefron 20mg.

Pregnancy ^UNSAFE

Lefron 20mg is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Kidney ^CAUTION

Lefron 20mg should be used with caution in patients with kidney disease. Dose adjustment of Lefron 20mg may be needed. Please consult your doctor.

Breast feeding ^{CONSULT YOUR DOCTOR}

Lefron 20mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Liver ^UNSAFE

Lefron 20mg is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Driving ^UNSAFE

Lefron 20mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Quick Tips

Lefron 20mg may increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
You have been prescribed Lefron 20mg to control the symptoms and slow down the progression of rheumatoid arthritis.
Get blood tests done every 4 weeks. This is to make sure that Lefron 20mg is not harming your liver or blood counts.
Avoid alcohol when taking Lefron 20mg as it could harm your liver.
Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Lefron 20mg.
It will take 6-8 weeks for Lefron 20mg to work. Hence, keep taking the medicine.
Tell your doctor if you experience nausea or diarrhea.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 631.
Leflunomide. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 1998 [Aug. 2015].
Leflunomide. Bridgewater, New Jersey: sanofi-aventis U.S; 2010.
CiplaMed. Leflunomide [Prescribing Information]. [Last Revised: 13 May 2020].
Central Drugs Standard Control Organisation. Leflunomide.
Memorial Sloan Kettering Cancer Center. Leflunomide. [last Updated: 12 Dec. 2022].
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 781-84.