Lupisoz Tablet


Product Info

Prescription required Yes
Marketer Lupin Ltd
Active Ingredient Esomeprazole (40mg)
Storage Store below 30°C
Chemical ClassSulfinylbenzimidazole Derivative
Habit FormingNo
Therapeutic ClassGASTRO INTESTINAL
Action ClassProton pump inhibitors
User Rating4.3
User Reviews393

FAQ

Question
Can I take Lupisoz with ranitidine?
Yes, Lupisoz can be taken with ranitidine. According to research reports, there are no significant interactions seen between Lupisoz and ranitidine. However, you must take them together only if prescribed by the doctor.
Answer

Question
Is Lupisoz safe to use?
Yes, Lupisoz is relatively safe to use. Most of the people who take Lupisoz do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefit.
Answer

Question
Can I take antacids along with Lupisoz?
Yes, you can take antacids along with Lupisoz. Take it 2 hours before or after you take Lupisoz.
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Question
Can I take Lupisoz for a long term?
Lupisoz is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Lupisoz may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Lupisoz as advised by your doctor and under their supervision.
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Question
What are the long term side effects of Lupisoz?
If Lupisoz is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
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Question
Can I take alcohol with Lupisoz?
No, alcohol intake is not advised with Lupisoz. Alcohol itself does not affect the working of Lupisoz, but it can increase the acid production. This may further cause worsening of your symptoms
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Question
Can Lupisoz cause weight gain?
Weight gain is reported in less than 1% of the patients taking Lupisoz but the exact cause is unknown. One possible explanation is higher food intake once the reflux symptoms are relieved. Lifestyle modifications such as proper diet and exercise can help to prevent weight gain.
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Question
Can I take Lupisoz with domperidone?
Yes, Lupisoz can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Lupisoz decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
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Question
Can I stop taking Lupisoz if I feel better?
If you have been taking Lupisoz for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Lupisoz.
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Question
What is the best time to take Lupisoz?
Usually, Lupisoz is taken once a day, first thing in the morning. If you take Lupisoz twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.
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Question
What if you forget to take Lupisoz?
If you miss a dose of Lupisoz, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Lupisoz Tablet Reviews

Lupisoz is used to treat conditions related to excessive stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. It reduces the amount of acid produced in the stomach and provides relief from symptoms and promotes healing.

Lupisoz can also be used to prevent stomach ulcers caused by certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Take the medicine as per your doctor's prescription. The dose will depend on what you are being treated for, but it is usually the lowest dose for the shortest time that is needed to treat your condition. It is usually taken on an empty stomach, preferably in the morning or at least 1 hour prior to meal. Continue taking the medicine even if your symptoms disappear until the doctor say it is okay to stop. If you are taking this medicine for a long time, your doctor may carry out regular tests to check your levels of magnesium which can fall with this medicine.

Common side effects include headache, constipation or diarrhea, stomach pain, and feeling or being sick. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. You may be more likely to have a broken bone if you take it for a long time. It is best to avoid foods that seem to make your symptoms worse, such as rich, spicy, and fatty foods. Cutting down on caffeinated drinks, such as tea, coffee, and cola, as well as alcohol may also help.

This medicine is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have had an allergic reaction to similar medicines in the past, or have osteoporosis. Alcohol does not interfere with the way Lupisoz works. However, drinking alcohol makes your stomach produce more acid than normal. This medicine can make you feel dizzy, sleepy, or affect your vision. If this happens, do not drive, cycle, or use machinery or tools until you feel better. It is not usually recommended during pregnancy and breastfeeding.

How Lupisoz Tablet Works

Lupisoz is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

How to Use Lupisoz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupisoz is to be taken empty stomach.

Benefits of Lupisoz Tablet

  • In Treatment of Gastroesophageal reflux disease (Acid reflux): GERD is a chronic (long-term) condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Lupisoz belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
  • In Treatment of Peptic ulcer disease: Lupisoz belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.
  • In Treatment of Zollinger-Ellison syndrome: Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Lupisoz By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.

Uses of Lupisoz Tablet

  • Treatment of Zollinger-Ellison syndrome
  • Treatment of Gastroesophageal reflux disease (Acid reflux)
  • Treatment of Peptic ulcer disease

Lupisoz Tablet Side Effects

Item form

Safety Tips

Alcohol  CAUTION
Caution is advised when consuming alcohol with Lupisoz. Please consult your doctor.
Liver  CAUTION
Lupisoz should be used with caution in patients with severe liver disease. Dose adjustment of Lupisoz may be needed. Please consult your doctor.However, no dose adjustment is required for patients with mild to moderate liver disease.
Pregnancy  CONSULT YOUR DOCTOR
Information regarding the use of Lupisoz during pregnancy is not available. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Lupisoz during breastfeeding is not available. Please consult your doctor.Caution should be exercised when Lupisoz is administered to breastfeeding women.
Driving  UNSAFE
Lupisoz may cause side effects which could affect your ability to drive.In rare cases, Lupisoz may cause dizziness and blurred vision, do not drive or use machines if you experience such symptoms.
Kidney  SAFE IF PRESCRIBED
Lupisoz is safe to use in patients with kidney disease. No dose adjustment of Lupisoz is recommended.However, due to lack of data, exercised should be caution in patients with severe renal insufficiency.

Quick Tips

  • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Avoid eating late at night or before bedtime.
  • Avoid alcohol and smoking.
  • Long-term use of Lupisoz can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Some healthy tips to prevent acidity from happening:Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.Avoid alcohol and smoking.Avoid eating late at night or before bedtime.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
  • It is a well-tolerated medicine and provides relief for a long time.

References

  1. Esomeprazole. Wilmington, DE: AstraZeneca Pharmaceuticals; 1989 [revised Dec. 2014].
  2. Central Drugs Standard Control Organisation (CDSCO).
  3. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011.
  4. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023.
  5. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023.
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Esomeprazole. [Updated 2019 Jun 3].

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