Migiplex 40mg/10mg Tablet


Product Info

Prescription required Yes
Marketer Arinna Lifescience Pvt Ltd
Active Ingredient Propranolol (40mg) + Flunarizine (10mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassCARDIAC
User Rating4.3
User Reviews584

FAQ

Question
Can Migiplex 40mg/10mg be used for the treatment of a migraine headache?
No, Migiplex 40mg/10mg does not help in relieving a migraine headache that has already started. It can only be used for preventing any new episode of migraine headaches.
Answer

Question
In which conditions is the use of Migiplex 40mg/10mg contraindicated?
Use of Migiplex 40mg/10mg is considered to be harmful for patients with allergy to any of the ingredients or excipients of this medicine. This medicine contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Since this medicine also contains flunarizine, the use of this medicine should be avoided in patients with the history of depression or Parkinson's disease.
Answer

Question
What are the instructions for the storage and disposal of Migiplex 40mg/10mg?
Keep Migiplex 40mg/10mg in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Answer

Question
Can I stop taking Migiplex 40mg/10mg when my symptoms are improved?
Migiplex 40mg/10mg is given as a prophylactic treatment for the prevention of migraine headaches. Do not stop taking this medicine until advised by your doctor as it may cause your migraine episodes to return. This medicine contains propranolol and a sudden withdrawal of propranolol may cause sweating, shaking, irregular or fast heartbeat, worsening of underlying angina or heart attack. You must take Migiplex 40mg/10mg exactly as advised by your doctor.
Answer
Question
What if you forget to take Migiplex Tablet?
If you miss a dose of Migiplex 40mg/10mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Migiplex 40mg/10mg Tablet Reviews

Migiplex 40mg/10mg is a combination of two medicines that helps in preventing migraine. This medicine is not used for treatment of acute migraine attack.

Migiplex 40mg/10mg should be taken on empty stomach, but try to have it same time regularly at a fixed time preferably at night. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.

Few common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness and cold extremities. It may cause sleepiness so try not to drive or do anything that requires mental focus or rise slowly while from sitting position. The drug has the ability to hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as blood pressure while taking this medicine.

Before taking this medicine, let your doctor know if you have liver or kidney, or depression disease, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

How Migiplex 40mg/10mg Tablet Works

Migiplex 40mg/10mg is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).

How to Use Migiplex 40mg/10mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migiplex 40mg/10mg is to be taken empty stomach.

Benefits of Migiplex 40mg/10mg Tablet

  • In Prevention of Migraine: Migiplex 40mg/10mg helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

Uses of Migiplex 40mg/10mg Tablet

  • Prevention of Migraine

Migiplex 40mg/10mg Tablet Side Effects

Item form

Safety Tips

Kidney  SAFE IF PRESCRIBED
Migiplex 40mg/10mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Migiplex 40mg/10mg may not be needed in these patients. Please consult your doctor.
Driving  UNSAFE
Migiplex 40mg/10mg may cause side effects which could affect your ability to drive.Migiplex 40mg/10mg may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Migiplex 40mg/10mg during breastfeeding is not available. Please consult your doctor.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Migiplex 40mg/10mg.
Liver  CAUTION
Migiplex 40mg/10mg should be used with caution in patients with liver disease. Dose adjustment of Migiplex 40mg/10mg may be needed. Please consult your doctor.Regular monitoring of blood pressure is advisable for dose adjustment.
Pregnancy  CONSULT YOUR DOCTOR
Migiplex 40mg/10mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Quick Tips

  • Do not take it to treat an acute attack of migraine.
  • Get sufficient sleep and avoid stress
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Migiplex 40mg/10mg affects you.
  • You have been prescribed Migiplex 40mg/10mg for prevention of migraine headaches.
  • Avoid chocolates,  cheese, processed food, alcohol and smoking
  • keep taking it regularly every day, even if you don't have any symptoms.
  • Have your meals at the same time everyday
  • Some tips that may help avoid a migraine attack:Have your meals at the same time everydayAvoid bright lights and extreme temperaturesAvoid loud music and noisy placesAvoid chocolates,  cheese, processed food, alcohol and smokingGet sufficient sleep and avoid stress
  • Avoid bright lights and extreme temperatures
  • It should be taken at night-time before going to bed.
  • Avoid loud music and noisy places

References

  1. Flunarizine. High Wycombe, Buckinghamshire: Janssen Cilag Ltd.; 2009 [revised Feb. 2014].
  2. Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings.
  3. Drugs.com. Flunarizine.

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