Mycotuf 250mg Tablet
Product Info
| Prescription required | Yes |
| Marketer | Cadila Pharmaceuticals Ltd |
| Active Ingredient | Ethionamide (250mg) |
| Storage | Store below 30°C |
| Chemical Class | Nicotinic acid derivatives |
| Habit Forming | No |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Mycobacterial cell wall inhibitors-Ethambutol |
| User Rating | 5.0 |
| User Reviews | 782 |
FAQ
What is Mycotuf 250mg? What is it used for?
Mycotuf 250mg is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.
For how long do I need to take Mycotuf 250mg?
Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.
Why has my doctor asked me to get blood tests done regularly?
The blood tests are done to check if your liver is functioning properly or not, since Mycotuf 250mg may affect your liver. Mycotuf 250mg can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.
Why is Mycotuf 250mg called a second line drug?
Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Mycotuf 250mg, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.
What are the symptoms which are suggestive of liver toxicity caused by Mycotuf 250mg?
If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.
Are there any precautions that I should take while taking Mycotuf 250mg so that I respond to the treatment?
It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Mycotuf 250mg. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).
Is it necessary to take pyridoxine with Mycotuf 250mg?
Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Mycotuf 250mg. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.
My friend is taking Mycotuf 250mg and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?
These changes could be due to Mycotuf 250mg or other medicines that she is taking for TB. Mycotuf 250mg may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.
What if you forget to take Mycotuf Tablet?
If you miss a dose of Mycotuf 250mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Mycotuf 250mg Tablet Reviews
Mycotuf 250mg is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
Mycotuf 250mg is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Mycotuf 250mg is usually given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.
Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
How Mycotuf 250mg Tablet Works
Mycotuf 250mg is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.
How to Use Mycotuf 250mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mycotuf 250mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Mycotuf 250mg Tablet
- In Tuberculosis (TB): Mycotuf 250mg is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Uses of Mycotuf 250mg Tablet
- Tuberculosis (TB)
Mycotuf 250mg Tablet Side Effects
Safety Tips
Liver
CAUTION
Mycotuf 250mg should be used with caution in patients with liver disease. Dose adjustment of Mycotuf 250mg may be needed. Please consult your doctor.Use of Mycotuf 250mg is not recommended in patients with the severe liver disease.
Kidney
SAFE IF PRESCRIBED
Mycotuf 250mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mycotuf 250mg may not be needed in these patients. Please consult your doctor.Dose adjustment may be needed in patients with end stage kidney disease.
Pregnancy
CONSULT YOUR DOCTOR
Mycotuf 250mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Alcohol
UNSAFE
It is unsafe to consume alcohol with Mycotuf 250mg.
Breast feeding
CONSULT YOUR DOCTOR
Mycotuf 250mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Mycotuf 250mg may cause side effects which could affect your ability to drive.Mycotuf 250mg may cause side effects such as drowsiness or a headache, that can impair your ability to drive.
Quick Tips
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
- Do not stop taking Mycotuf 250mg even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.
- Avoid consuming alcohol while taking this medication.
- It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
- Take it with food to avoid stomach upset.
- It has to be taken for several months in order for it work properly (usually 6 months).
- Mycotuf 250mg is effective at treating tuberculosis when taken together with other antibacterial drugs.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
- Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016.
- Drugs.com. Ethionamide.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.