Nextki 50mg Tablet
Product Info
| Prescription required | Yes |
| Marketer | Emcure Pharmaceuticals Ltd |
| Active Ingredient | Dasatinib (50mg) |
| Storage | Store below 30°C |
| Chemical Class | Pyrimidine and Thiazole Derivetive |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| User Rating | 4.8 |
| User Reviews | 673 |
FAQ
What if you forget to take Nextki Tablet?
If you miss a dose of Nextki 50mg, skip it and continue with your normal schedule. Do not double the dose.
Nextki 50mg Tablet Reviews
Nextki 50mg is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
Nextki 50mg can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.
Nextki 50mg can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.
How Nextki 50mg Tablet Works
Nextki 50mg is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
How to Use Nextki 50mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nextki 50mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Nextki 50mg Tablet
- In Blood cancer (Chronic myeloid leukaemia): Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Nextki 50mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Nextki 50mg Tablet
- Blood cancer (Chronic myeloid leukaemia)
Nextki 50mg Tablet Side Effects
Safety Tips
Pregnancy
CONSULT YOUR DOCTOR
Nextki 50mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Nextki 50mg is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nextki 50mg may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Nextki 50mg is safe to use in patients with liver disease. No dose adjustment of Nextki 50mg is recommended.
Breast feeding
UNSAFE
Nextki 50mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nextki 50mg. Please consult your doctor.
Driving
UNSAFE
Nextki 50mg may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with Nextki 50mg.
Quick Tips
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Take it with or without food, preferably at the same time each day.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 361-62.
- Drugs.com. Dasatinib Pregnancy and Breastfeeding Warnings.
- Central Drugs Standard Control Organisation (CDSCO).
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dasatinib. [Updated 2018 Dec 3].
- Dasatinib monohydrate. Dublin, Ireland: Bristol-Myers Squibb Pharma; 2006 [revised 06 Feb. 2019].