Nikoran 10 Tablet


Product Info

Prescription required Yes
Marketer Torrent Pharmaceuticals Ltd
Active Ingredient Nicorandil (10mg)
Storage Store in a refrigerator (2 - 8°C). Do not freeze.
Chemical ClassNicotinamides Derivatives
Habit FormingNo
Therapeutic ClassCARDIAC
Action ClassPotassium channel opener
User Rating4.5
User Reviews633

FAQ

Question
Can I take Nikoran 10 if I am taking aspirin?
You should avoid taking Nikoran 10 and aspirin together. Taking the two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor, If you notice blood in your stool or vomit while using Nikoran 10.
Answer

Question
What class of drug is Nikoran 10 and what is it used for?
Nikoran 10 belongs to a class of medicines known as “potassium channel openers”. It causes widening of the arteries. This decreases the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta-blockers, calcium channel antagonist) meant for angina.
Answer

Question
How long does it take Nikoran 10 to start working?
Nikoran 10 starts working after about an hour of taking the medicine, but full benefits may be seen only after 4 to 5 days.
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Question
Can I stop taking Nikoran 10?
No, you should not stop taking Nikoran 10 without speaking to your doctor first. If you stop Nikoran 10 suddenly, your anginal pain may recur. Talk to your doctor if you are experiencing any side effects.
Answer

Question
Can Nikoran 10 affect my sex life?
No, Nikoran 10 does not affect your sex life. However, it is not recommended to take medicines used to treat erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine) while taking Nikoran 10. Taking them together can lead to a serious drop in your blood pressure.
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Question
For how long do I need to continue Nikoran 10?
Continue taking your medicine for as long as your doctor tells you. Nikoran 10 is generally prescribed for a long term. You may even need to take it for the rest of your life.
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Question
Who should not use Nikoran 10?
People who are allergic to Nikoran 10 or any of its ingredients should avoid using this medicine. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Nikoran 10. Additionally, patients taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil, and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat) should not use the medication. Your blood pressure may be affected if these medicines are taken with Nikoran 10 or if you have low blood volume.
Answer

Question
What if somebody accidentally takes excess of Nikoran 10?
He or she should be taken to the hospital immediately. The person may experience signs of low blood pressure, which include feeling weak or dizzy. He or she may also experience irregular or fast heart beat.
Answer
Question
What if you forget to take Nikoran Tablet?
If you miss a dose of Nikoran 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Answer

Nikoran 10 Tablet Reviews

Nikoran 10 is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are either not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.

Nikoran 10 may be taken with or without food. It should be swallowed whole with water. Take this medicine regularly and at about the same time(s) each day. Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working. Do not stop taking it without talking to our doctor as sudden withdrawal may cause your chest pain to come back. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, exercising regularly, and managing stress.

The most common side effect of this medicine is headache, especially during the first few days of treatment. This usually improves within a week. However,  drinking plenty of fluids and avoiding alcohol may help. Other common side effects include dizziness or weakness, nausea, and flushing (sense of warmth in the face, ears, neck, and trunk). Talk to your doctor if these bother you or do not go away.

Nikoran 10 may not be suitable for some people. Inform your doctor if you have a history of low blood pressure or heart failure. Also let your doctor know about all other medications that you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. Nikoran 10 is not usually recommended during pregnancy or breastfeeding.

How Nikoran 10 Tablet Works

Nikoran 10 is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. It also relaxes coronary artery (that carries blood to heart). This reduces the frequency and severity of angina attacks.

How to Use Nikoran 10 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nikoran 10 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Nikoran 10 Tablet

  • In Treatment of Angina (heart-related chest pain): Nikoran 10 helps in prevention as well as treatment of angina. Angina is a chest pain that is usually caused by the narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nikoran 10 relaxes and widens the blood vessels so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes thereby improving your ability to exercise and go about your daily life more easily. This medicine needs to be taken regularly to be effective so keep taking it even if you are not having any angina symptoms.

Uses of Nikoran 10 Tablet

  • Treatment of Angina (heart-related chest pain)

Nikoran 10 Tablet Side Effects

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Safety Tips

Alcohol  UNSAFE
It is unsafe to consume alcohol with Nikoran 10.
Breast feeding  CONSULT YOUR DOCTOR
Nikoran 10 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy  CONSULT YOUR DOCTOR
Nikoran 10 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Liver  SAFE IF PRESCRIBED
Nikoran 10 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nikoran 10 may not be needed in these patients. Please consult your doctor.
Kidney  SAFE IF PRESCRIBED
Nikoran 10 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nikoran 10 may not be needed in these patients. Please consult your doctor.
Driving  UNSAFE
Nikoran 10 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Quick Tips

  • Nikoran 10 may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
  • Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Nikoran 10 as it may cause low blood pressure.
  • Do not consume alcohol while taking Nikoran 10 as that may cause increased dizziness.
  • You must continue to take it as advised, usually for a long time.
  • Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.
  • Nikoran 10 may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.

References

  1. Central Drugs Standard Control Organisation (CDSCO).
  2. Nicorandil. Guildford, Surrey: SANOFI; 2009 [revised 16 Mar. 2018].
  3. Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 198.
  4. Nicorandil [patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.
  5. Nicorandil. Macquarie Park, New South Wales: Sanofi-Aventis Australia Pty Ltd.; 2017.
  6. National Health Service. Nicorandil; 2019.
  7. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 57.

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