Nublexa Tablet
Product Info
| Prescription required | Yes |
| Marketer | Bayer Zydus Pharma Pvt Ltd |
| Active Ingredient | Regorafenib (40mg) |
| Storage | Store below 30°C |
| Chemical Class | Diarylethers Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| User Rating | 4.9 |
| User Reviews | 574 |
FAQ
Is Nublexa chemotherapy?
Yes, Nublexa is used as a chemotherapy to treat cancer of stomach (gastrointestinal stromal tumors), colon or rectal, in cases who have been treated with other cancer treatments or are incurable with other treatments.
Does Nublexa shrink tumors?
Yes, Nublexa works either by shrinking the tumor or stops it from growing further.
How is Nublexa administered?
Nublexa needs to be administered orally as advised by your doctor. It is to be taken at the same time of the day, with food.
Nublexa Tablet Reviews
Nublexa is a Tyrosine kinase inhibitors used in the treatment of cancer of colon and rectum.
Nublexa should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include infection, low blood platelets, anemia, decreased appetite, hemorrhage, and high blood pressure. It can also cause voice change, diarrhea, stomatitis, vomiting, nausea, bilirubin in urine, increased liver enzyme, rash, weakness, pain, fever, mucosal inflammation, and weight loss. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Nublexa should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include infection, low blood platelets, anemia, decreased appetite, hemorrhage, and high blood pressure. It can also cause voice change, diarrhea, stomatitis, vomiting, nausea, bilirubin in urine, increased liver enzyme, rash, weakness, pain, fever, mucosal inflammation, and weight loss. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
How Nublexa Tablet Works
Nublexa is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
How to Use Nublexa Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nublexa is to be taken with food.
Benefits of Nublexa Tablet
- In Cancer of colon and rectum: Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Nublexa treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
Uses of Nublexa Tablet
- Cancer of colon and rectum
Nublexa Tablet Side Effects
Safety Tips
Liver
CAUTION
Nublexa should be used with caution in patients with liver disease. Dose adjustment of Nublexa may be needed. Please consult your doctor.Regular monitoring of liver function tests is advised while you are taking this medicine. Use of Nublexa is not recommended in patients with the severe liver disease.
Pregnancy
CONSULT YOUR DOCTOR
Nublexa is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Nublexa alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Breast feeding
CONSULT YOUR DOCTOR
Nublexa is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Kidney
SAFE IF PRESCRIBED
Nublexa is safe to use in patients with kidney disease. No dose adjustment of Nublexa is recommended.However, limited information is available on use of Nublexa in patients with severe kidney disease.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nublexa. Please consult your doctor.
Quick Tips
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
- Nublexa is used in the treatment of cancers of colon and rectum.
- Take it with food, preferably at the same time each day.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
References
- Drugs.com. Regorafenib Pregnancy and Breastfeeding Warnings.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1203-204.
- Central Drugs Standard Control Organisation (CDSCO).