P-Nolzine 500mg Tablet SR
Product Info
| Prescription required | Yes |
| Marketer | Pacific Meditech Pvt Ltd |
| Active Ingredient | Ranolazine (500mg) |
| Storage | Store below 30°C |
| Chemical Class | Acetanilide & piperazine derivative |
| Habit Forming | No |
| Therapeutic Class | CARDIAC |
| Action Class | Late Sodium channel blocker- angina |
| User Rating | 4.4 |
| User Reviews | 316 |
FAQ
Is it safe to take P-Nolzine 500mg if I am already taking metoprolol?
Yes, it is safe to take the P-Nolzine 500mg and Metoprolol together. P-Nolzine 500mg has minimal effect on blood pressure in patients with angina.
What are the serious side effects of P-Nolzine 500mg?
P-Nolzine 500mg may cause changes in the electrical activity of the heart which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint, lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. P-Nolzine 500mg may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.
I started taking P-Nolzine 500mg about a week ago. Now I have noticed that my urine has become very dark though I am taking plenty of fluids. Is there anything to worry about?
Urine discoloration could be because of P-Nolzine 500mg. You need not worry if you do not have any other symptoms. However, if it still bothers you, you can talk to your doctor who will advise you further.
I am a diabetic and am taking metformin. My doctor has prescribed P-Nolzine 500mg, is it safe to take both together?
If you are taking metformin along with P-Nolzine 500mg, you have to be careful since P-Nolzine 500mg may increase the levels of metformin in the body which can lead to metformin toxicity. Talk to your doctor who will modify the dose of metformin.
I have been taking simvastatin to keep my cholesterol levels in check. Can I take P-Nolzine 500mg with it?
It is recommended not to take simvastatin and P-Nolzine 500mg together because it may cause simvastatin toxicity which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take, then take it exactly as advised by the doctor.
In case I accidentally take an excess of P-Nolzine 500mg, what will happen?
Excess of P-Nolzine 500mg can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking and you can even faint. If you have taken an excess of P-Nolzine 500mg by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.
What if you forget to take P-Nolzine Tablet SR?
If you miss a dose of P-Nolzine 500mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
P-Nolzine 500mg Tablet SR Reviews
P-Nolzine 500mg is used for the management of angina (heart-related chest pain). It helps to prevent new attacks of angina but does not stop an acute attack, once started. It relieves chest pain by making the heart work more efficiently.
P-Nolzine 500mg should be taken in the dose as advised by your doctor, at the same time each day. It should be taken with food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm. If you stop taking it, your chest pain may come back.
You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, vomiting, headache, dizziness, constipation, and weakness. Talk to your doctor if these bother you or do not go away.
P-Nolzine 500mg may not suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.
P-Nolzine 500mg should be taken in the dose as advised by your doctor, at the same time each day. It should be taken with food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm. If you stop taking it, your chest pain may come back.
You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, vomiting, headache, dizziness, constipation, and weakness. Talk to your doctor if these bother you or do not go away.
P-Nolzine 500mg may not suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.
How P-Nolzine 500mg Tablet SR Works
P-Nolzine 500mg is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.
How to Use P-Nolzine 500mg Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. P-Nolzine 500mg is to be taken with food.
Benefits of P-Nolzine 500mg Tablet SR
- In Treatment of Angina (heart-related chest pain): P-Nolzine 500mg reduces the oxygen requirement of the heart and relaxes the heart muscles. It makes sure that your heart is able to perform its functions in the amount of oxygen supply available without causing stress on heart muscles. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.
Uses of P-Nolzine 500mg Tablet SR
- Treatment of Angina (heart-related chest pain)
P-Nolzine 500mg Tablet SR Side Effects
Safety Tips
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with P-Nolzine 500mg. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
P-Nolzine 500mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Kidney
CAUTION
P-Nolzine 500mg should be used with caution in patients with kidney disease. Dose adjustment of P-Nolzine 500mg may be needed. Please consult your doctor.Use of P-Nolzine 500mg is not recommended in patients with severe kidney disease.
Driving
CONSULT YOUR DOCTOR
It is not known whether P-Nolzine 500mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Pregnancy
CONSULT YOUR DOCTOR
P-Nolzine 500mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Liver
CAUTION
P-Nolzine 500mg should be used with caution in patients with liver disease. Dose adjustment of P-Nolzine 500mg may be needed. Please consult your doctor.Use of P-Nolzine 500mg is not recommended in patients with moderate to severe liver disease.
Quick Tips
- Notify your doctor if you are taking any other medications along with P-Nolzine 500mg
- It improves HbA1c and blood sugar levels in diabetes patients.
- It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- It should be taken with food to avoid stomach upset.
References
- Ranolazine. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 22 Nov. 2018].
- Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
- Ranolazine. Foster City, California: Gilead Sciences, Inc.; 2013.
- Central Drugs Standard Control Organisation (CDSCO).
- Ranolazine Sustained Release Tablets [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2019.