Paincom-DT Tablet
Product Info
| Prescription required | Yes |
| Marketer | Biochem Pharmaceutical Industries |
| Active Ingredient | Piroxicam (20mg) |
| Storage | Store below 30°C |
| Chemical Class | Enolic acid Derivatives |
| Habit Forming | No |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids) |
| User Rating | 4.2 |
| User Reviews | 363 |
FAQ
Can Paincom-DT lead to skin reactions?
Yes. Paincom-DT is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Can Paincom-DT be used along with dexamethasone?
No. Paincom-DT should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Can Paincom-DT lead to difficulty in conception?
Yes. Paincom-DT can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Are there any alternatives of Paincom-DT?
Yes. There are alternatives to Paincom-DT. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Is Paincom-DT effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Paincom-DT as the cause of back pain can be different for different person.
Can Paincom-DT be used with methocarbamol?
Yes. Methocarbamol can be used with Paincom-DT as no serious side effects are known. Inform your doctor before starting any of the medication.
What is the difference between Paincom-DT and meloxicam?
Both Paincom-DT and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Paincom-DT.
Can Paincom-DT be used in the treatment of allergy?
No. Paincom-DT is not a drug to treat allergy. It is a pain killer.
Can I use Paincom-DT if I am a diabetic?
Paincom-DT in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Paincom-DT so taking piroxicam can lead to increased risk of renal failure by many folds.
How long does Paincom-DT work?
Paincom-DT is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Can I use Paincom-DT if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Paincom-DT?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Is Paincom-DT a blood thinner?
No. Paincom-DT is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
What are the serious side effects of Paincom-DT?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
What is the difference between Paincom-DT and ketoprofen?
Both Paincom-DT and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Paincom-DT. Ketoprofen gel also showed excellent tolerability.
Are Paincom-DT and aspirin same?
No. Paincom-DT and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can Paincom-DT be used with lithium?
No. Paincom-DT should not be used with lithium. Paincom-DT leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Can Paincom-DT be used with Lisinopril?
No. Paincom-DT should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Paincom-DT.
What increases the chances of getting a gastric ulcer when I am already taking Paincom-DT?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Can Paincom-DT be used along with Losartan?
No. Paincom-DT should not be combined with Losartan. It is important to note that Paincom-DT decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Paincom-DT.
Is Paincom-DT a muscle relaxant?
No. Paincom-DT is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Can Paincom-DT be used with warfarin?
No. Paincom-DT should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Can I use Paincom-DT if I have a deranged renal function?
No. Paincom-DT should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Why is beta cyclodextrin added to Paincom-DT?
Yes. Paincom-DT can be combined with beta-cyclodextrin. Research has shown that combining Paincom-DT with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Can Paincom-DT be used along with paracetamol?
Yes. Paracetamol can be used with Paincom-DT as no serious side effects are known. Inform your doctor before starting any of the medication.
What are the contraindications for Paincom-DT?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Is Paincom-DT a sulfa drug?
Paincom-DT is a sulphur containing compound. Paincom-DT can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Can I use Paincom-DT if I have peptic ulcer disease?
No. Paincom-DT is contraindicated in cases of active peptic ulcer disease. Paincom-DT is known to cause gastric ulceration and bleeding.
Can you donate blood when on the medication with Paincom-DT?
Yes. You can donate blood when on Paincom-DT. Do inform your doctor before donating blood.
What is the difference between Paincom-DT and tramadol?
Paincom-DT is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
What is the difference between Paincom-DT and nimesulide?
Both Paincom-DT and nimesulide are pain killers. However, Paincom-DT is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Is Paincom-DT affective in gout management?
Yes. Paincom-DT can be given for the treatment of acute gout. Research studies have shown Paincom-DT to be highly effective in the treatment of acute gout.
Can I use Paincom-DT for a migraine?
Paincom-DT is not approved for the treatment of migraine. Research studies have shown that Paincom-DT is effective in significantly decreasing the pain associated with migraine without aura.
Can Paincom-DT be used to treat menstrual cramp?
Paincom-DT is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Can Paincom-DT be used with Tizanidine?
Yes, Paincom-DT can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
What is the difference between Paincom-DT and naproxen?
Both Paincom-DT and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Paincom-DT.
Can Paincom-DT be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Paincom-DT or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Paincom-DT.
Can Paincom-DT be used with diuretics?
No. Paincom-DT should not be used with diuretics. Paincom-DT reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can you get high by using Paincom-DT?
No. Paincom-DT is not known to cause high. It is a non-narcotic painkiller.
Is Paincom-DT a NSAID?
Yes. Paincom-DT is a non-steroidal anti-inflammatory drug (NSAID).
Is Paincom-DT a narcotic?
No. Paincom-DT is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Can I use Paincom-DT if I am pregnant?
No. Paincom-DT should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Can Paincom-DT be used with calcium channel blocker?
Yes. Paincom-DT can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
What is the difference between Paincom-DT and diclofenac?
Both Paincom-DT and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Paincom-DT.
Can Paincom-DT be used in hypertension?
No. Paincom-DT is not a medication to control hypertension. It is important to note that Paincom-DT decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Paincom-DT.
What if you forget to take Paincom Tablet DT?
If you miss a dose of Paincom-DT, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Paincom-DT Tablet Reviews
Paincom-DT is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.
Paincom-DT should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, headache, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
How Paincom-DT Tablet Works
Paincom-DT is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
How to Use Paincom-DT Tablet
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Paincom-DT is to be taken with food.
Benefits of Paincom-DT Tablet
- In Pain relief: Paincom-DT is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Uses of Paincom-DT Tablet
- Pain relief
Paincom-DT Tablet Side Effects
Safety Tips
Pregnancy
CONSULT YOUR DOCTOR
Paincom-DT is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Paincom-DT is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Paincom-DT may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Paincom-DT should be used with caution in patients with severe kidney disease. Dose adjustment of Paincom-DT may be needed. Please consult your doctor.
Alcohol
UNSAFE
It is unsafe to consume alcohol with Paincom-DT.
Liver
CAUTION
Paincom-DT should be used with caution in patients with liver disease. Dose adjustment of Paincom-DT may be needed. Please consult your doctor.
Quick Tips
- Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
- Paincom-DT helps relieve pain and swelling of various joints and muscles.
- Take it with food to avoid stomach upset.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
References
- Piroxicam. Feb. 2015.
- Piroxicam [Drug Label]. Mumbai, India: Pfizer Limited; 2022.
- PubChem. Piroxicam.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
- ScienceDirect. Piroxicam.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
- Central Drugs Standard Control Organisation (CDSCO).
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.