Plessi 0.125 Tablet
Product Info
| Prescription required | Yes |
| Marketer | Consern Pharma Limited |
| Active Ingredient | Pramipexole (0.125mg) |
| Storage | Store below 30°C |
| Chemical Class | Benzothiazole Derivative |
| Habit Forming | No |
| Therapeutic Class | NEURO CNS |
| Action Class | Dopamine agonists |
| User Rating | 4.7 |
| User Reviews | 533 |
FAQ
Can I stop taking Plessi 0.125 if my symptoms of Parkinson’s disease have improved?
You should not stop Plessi 0.125 without talking to your doctor. Sudden discontinuation of Plessi 0.125 may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.
Is Plessi 0.125 a muscle relaxant?
No, Plessi 0.125 is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.
How does Plessi 0.125 work for restless legs?
Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. Plessi 0.125 belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.
Does Plessi 0.125 cause weight gain?
A common side effect of Plessi 0.125 is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.
Does Plessi 0.125 make you sleepy?
Yes, Plessi 0.125 may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.
What are the serious side effects of Plessi 0.125?
The serious side effects of Plessi 0.125 include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.
How should Plessi 0.125 be taken?
You should take Plessi 0.125 as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.
What are impulse control disorders caused by Plessi 0.125?
Plessi 0.125 may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. Plessi 0.125 may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.
What if you forget to take Plessi Tablet?
If you miss a dose of Plessi 0.125, skip it and continue with your normal schedule. Do not double the dose.
Plessi 0.125 Tablet Reviews
Plessi 0.125 is used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.
Plessi 0.125 should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.
Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble, or uncontrolled spending as these may prove very harmful.
Plessi 0.125 should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.
Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble, or uncontrolled spending as these may prove very harmful.
How Plessi 0.125 Tablet Works
Plessi 0.125 works by mimicking the action of dopamine, a chemical messenger that is needed to control movement in the brain.
How to Use Plessi 0.125 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Plessi 0.125 is to be taken with food.
Benefits of Plessi 0.125 Tablet
- In Restless leg syndrome: Restless leg syndrome is a condition that causes an uncontrollable urge to move your legs, usually because of an uncomfortable sensation. It typically happens in the evening or nighttime hours when you're sitting or lying down. Moving or walking, that is change in posture, will control the unpleasant feeling temporarily. Plessi 0.125 helps to relieve this uncomfortable urge and calms these sensations. Take it as advised by the doctor to get the maximum relief.
- In Parkinson's disease: Plessi 0.125 is effective in relieving symptoms of Parkinson's disease such as tremors, muscle stiffness, and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in the coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.
Uses of Plessi 0.125 Tablet
- Restless leg syndrome
- Parkinson's disease
Plessi 0.125 Tablet Side Effects
Safety Tips
Kidney
CAUTION
Plessi 0.125 should be used with caution in patients with kidney disease. Dose adjustment of Plessi 0.125 may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Plessi 0.125 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Plessi 0.125 may not be needed in these patients. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Plessi 0.125 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Plessi 0.125 suppresses serum prolactin and may interfere with breastfeeding.
Alcohol
UNSAFE
Plessi 0.125 may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Plessi 0.125 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving
UNSAFE
Plessi 0.125 may cause side effects which could affect your ability to drive.Plessi 0.125 can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.
Quick Tips
- You have been prescribed Plessi 0.125 to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
- Talk to your doctor in case you develop hallucinations or other changes in your behavior.
- For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
- Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
- Do not stop taking the medication suddenly without talking to your doctor.
- Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
- When you first start taking Plessi 0.125, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- It can be taken with or without food. Taking it with food may reduce nausea.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1140-41.
- Pramipexole dihydrochloride [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021.
- Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
- Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 475-76.
- Central Drugs Standard Control Organisation (CDSCO).
- Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 7 Feb. 2018].