Pramirise 0.25mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Arinna Lifescience Pvt Ltd
Active Ingredient	Pramipexole (0.25mg)
Storage	Store below 30°C
Chemical Class	Benzothiazole Derivative
Habit Forming	No
Therapeutic Class	NEURO CNS
Action Class	Dopamine agonists
User Rating	4.7
User Reviews	715

FAQ

Does Pramirise 0.25mg cause weight gain?

A common side effect of Pramirise 0.25mg is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.

How does Pramirise 0.25mg work for restless legs?

Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. Pramirise 0.25mg belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.

Does Pramirise 0.25mg make you sleepy?

Yes, Pramirise 0.25mg may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.

What are impulse control disorders caused by Pramirise 0.25mg?

Pramirise 0.25mg may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. Pramirise 0.25mg may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.

What are the serious side effects of Pramirise 0.25mg?

The serious side effects of Pramirise 0.25mg include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.

Is Pramirise 0.25mg a muscle relaxant?

No, Pramirise 0.25mg is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.

Can I stop taking Pramirise 0.25mg if my symptoms of Parkinson’s disease have improved?

You should not stop Pramirise 0.25mg without talking to your doctor. Sudden discontinuation of Pramirise 0.25mg may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.

How should Pramirise 0.25mg be taken?

You should take Pramirise 0.25mg as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.

What if you forget to take Pramirise Tablet?

If you miss a dose of Pramirise 0.25mg, skip it and continue with your normal schedule. Do not double the dose.

Pramirise 0.25mg Tablet Reviews

Pramirise 0.25mg is used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.

Pramirise 0.25mg should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.

Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble, or uncontrolled spending as these may prove very harmful.

How Pramirise 0.25mg Tablet Works

Pramirise 0.25mg works by mimicking the action of dopamine, a chemical messenger that is needed to control movement in the brain.

How to Use Pramirise 0.25mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pramirise 0.25mg is to be taken with food.

Benefits of Pramirise 0.25mg Tablet

In Restless leg syndrome: Restless leg syndrome is a condition that causes an uncontrollable urge to move your legs, usually because of an uncomfortable sensation. It typically happens in the evening or nighttime hours when you're sitting or lying down. Moving or walking, that is change in posture, will control the unpleasant feeling temporarily. Pramirise 0.25mg helps to relieve this uncomfortable urge and calms these sensations. Take it as advised by the doctor to get the maximum relief.
In Parkinson's disease: Pramirise 0.25mg is effective in relieving symptoms of Parkinson's disease such as tremors, muscle stiffness, and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in the coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Uses of Pramirise 0.25mg Tablet

Restless leg syndrome
Parkinson's disease

Pramirise 0.25mg Tablet Side Effects

Safety Tips

Kidney ^CAUTION

Pramirise 0.25mg should be used with caution in patients with kidney disease. Dose adjustment of Pramirise 0.25mg may be needed. Please consult your doctor.

Liver ^{SAFE IF PRESCRIBED}

Pramirise 0.25mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pramirise 0.25mg may not be needed in these patients. Please consult your doctor.

Breast feeding ^{CONSULT YOUR DOCTOR}

Pramirise 0.25mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Pramirise 0.25mg suppresses serum prolactin and may interfere with breastfeeding.

Pregnancy ^{CONSULT YOUR DOCTOR}

Pramirise 0.25mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Alcohol ^UNSAFE

Pramirise 0.25mg may cause excessive drowsiness with alcohol.

Driving ^UNSAFE

Pramirise 0.25mg may cause side effects which could affect your ability to drive.Pramirise 0.25mg can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.

Quick Tips

Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
When you first start taking Pramirise 0.25mg, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
You have been prescribed Pramirise 0.25mg to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
Do not stop taking the medication suddenly without talking to your doctor.
Talk to your doctor in case you develop hallucinations or other changes in your behavior.
Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
It can be taken with or without food. Taking it with food may reduce nausea.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1140-41.
Pramipexole dihydrochloride [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021.
Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 475-76.
Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 7 Feb. 2018].
Central Drugs Standard Control Organisation (CDSCO).
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010.