Prolet 12.5 Tablet
Product Info
| Prescription required | Yes |
| Marketer | Alteus Biogenics Pvt Ltd |
| Active Ingredient | Primidone (12.5mg) |
| Storage | Store below 30°C |
| Chemical Class | Barbituric Acid Derivative |
| Habit Forming | Yes |
| Therapeutic Class | NEURO CNS |
| Action Class | Barbiturate |
| User Rating | 4.2 |
| User Reviews | 305 |
FAQ
Is Prolet 12.5 habit forming?
Yes, if you use Prolet 12.5 for a long time, you may become dependent on it. Moreover, stopping the medicine suddenly may also lead to withdrawal symptoms. Therefore, you must inform your doctor before stopping the Prolet 12.5.
How should I store this medicine?
Keep it in a cool dry place where the temperature stays below 25°C. Do not leave it on a windowsill or in the car on hot days. Keep it out of reach of children.
Can Prolet 12.5 cause headache?
Though headache is not a very common side effect of Prolet 12.5, it can occur in a few patients.
Can I take Prolet 12.5 and propranolol together?
While taking propranolol and Prolet 12.5 together, your blood pressure should be monitored as Prolet 12.5 may interfere with working of propranolol. Your doctor may modify your dose if needed.
What are the serious side effects of using Prolet 12.5? How can I check for these side effects?
Severe allergic reactions, skin reactions, abnormalities in blood cells, and worsening of seizures are some of the serious side effects of Prolet 12.5. Severe allergic reactions may result in difficulty in breathing, swelling of the lips, tongue, face, or hives. Skin reactions may cause redness, pain, ulcers, blisters, shedding the outer layer of skin. If you have an abnormality of the blood cells, your skin may appear pale. Additionally you may suffer from abnormal bleeding or frequent bruising, fever, or sore throat.
What should I avoid while taking Prolet 12.5?
If Prolet 12.5 makes you feel sleepy, avoid driving or operating heavy machinery. Alcohol consumption should be avoided since taking both together may cause excessive sleepiness. You should avoid getting pregnant since Prolet 12.5 is associated with an increased risk of abnormalities in babies.
Does Prolet 12.5 affect blood pressure?
No, Prolet 12.5 does not have any effect on blood pressure.
Can I stop taking Prolet 12.5?
Do not stop taking Prolet 12.5 even if you are feeling well, unless your doctor advises so. Suddenly stopping Prolet 12.5 may cause unwanted effects commonly known as withdrawal symptoms. To prevent this, the dose of Prolet 12.5 needs to be reduced gradually before completely stopping it.
What should I tell my doctor before taking this medicine?
Inform your doctor if you are taking any other medicines including medicines for epilepsy or seizures, medicines used to thin your blood (e.g., warfarin), birth control pills, medicines to control bacterial infection (e.g., chloramphenicol, metronidazole, and doxycycline), medicines to control viral infection (e.g., nelfinavir), and asthma medicines (e.g., theophylline and montelukast), etc. Also, inform your doctor if you are planning to become pregnant or are breastfeeding. Further, you should tell the doctor if you have ever had liver problems, kidney problems, lung problems, or porphyria (a rare blood pigment disorder).
Prolet 12.5 Tablet Reviews
Prolet 12.5 belongs to a class of medicines called barbiturates. It is used to treat and prevent epilepsy (seizures). They also have hypnotic properties. This means, they slow down the activity of the brain and can make you feel sleepy or dizzy.
Prolet 12.5 may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it may be habit-forming with long-term use. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better.
Some common side effects of this medicine include nausea, vomiting, vertigo, low energy, impaired coordination, visual disturbance, and headache. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Remember to consult your doctor if you notice severe rashes, especially accompanied by fever after taking this medicine. It should be noted that long-term use of this medicine can cause pain in joints also.
Prolet 12.5 may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it may be habit-forming with long-term use. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better.
Some common side effects of this medicine include nausea, vomiting, vertigo, low energy, impaired coordination, visual disturbance, and headache. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Remember to consult your doctor if you notice severe rashes, especially accompanied by fever after taking this medicine. It should be noted that long-term use of this medicine can cause pain in joints also.
How Prolet 12.5 Tablet Works
Prolet 12.5 is a barbiturate. It controls seizures or fits by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.
How to Use Prolet 12.5 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prolet 12.5 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Prolet 12.5 Tablet
- In Epilepsy/Seizures: Prolet 12.5 slows down electrical signals in the brain that cause seizures (fits). It can also help reduce symptoms of seizures, such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Therefore, do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Uses of Prolet 12.5 Tablet
- Epilepsy/Seizures
Prolet 12.5 Tablet Side Effects
Safety Tips
Driving
UNSAFE
Prolet 12.5 may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Prolet 12.5 should be used with caution in patients with kidney disease. Dose adjustment of Prolet 12.5 may be needed. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Prolet 12.5 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Prolet 12.5 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Baby should be monitored for excessive sleepiness and weight gain.
Liver
CAUTION
Prolet 12.5 should be used with caution in patients with liver disease. Dose adjustment of Prolet 12.5 may be needed. Please consult your doctor.
Alcohol
UNSAFE
Prolet 12.5 may cause excessive drowsiness with alcohol.
Quick Tips
- Practice yoga every day.
- Do not stop taking the medication suddenly, as it can reverse the seizures.
- Some healthy tips to prevent seizures:Take a healthy diet along with regular exercise.Practice yoga every day.Get enough sleep at nighttime.Limit the use of screen time such as mobile/ laptop.Take your medication on time.
- Take your medication on time.
- Take a healthy diet along with regular exercise.
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Your doctor may get regular tests done to monitor the level of blood cells in your blood while taking this medication.
- It makes you feel dizzy and drowsy. Avoid driving and activity requiring mental focus until you know how this medicine affects you.
- Limit the use of screen time such as mobile/ laptop.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Inform your doctor if you notice mood changes and suicidal thoughts while taking Prolet 12.5.
- Get enough sleep at nighttime.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1150-51.
- Primidone. Paris, France: SERB; 2010 [revised 5 Aug. 2014].
- Drugs.com. Primidone.
- Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 407-408.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Primidone. [Updated 2018 Oct 31].
- Primidone. Warriewood, New South Wales: Link Medical Products Pty Ltd.; 2014.