Prulitop 2 Tablet


Product Info

Prescription required Yes
Marketer Alniche Life Sciences Pvt Ltd
Active Ingredient Prucalopride (2mg)
Storage Store below 30°C
Chemical ClassDihydrobenzofurancarboxamide Derivative {benzamides}
Habit FormingNo
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin (5-HT4) receptor agonist-Prokinetic agent
User Rating4.1
User Reviews379

FAQ

Question
How quickly does Prulitop 2 work?
Prulitop 2 has been found to act rapidly but the effect varies from person to person. This is because the response to a particular medication varies in every patient. Usually, the medicine generates a bowel movement within 2-3 hours. However, it may take about 4-5 days to show complete effect and rapid bowel movements.
Answer

Question
When should I avoid taking Prulitop 2?
You should avoid taking Prulitop 2 if you are allergic to it. It should also be avoided if you have a tear in your stomach or intestinal wall, a bowel blockage or inflammatory conditions of the intestinal wall like Crohn’s disease or ulcerative colitis. Always consult your doctor before starting the medication. The doctor should be informed about any ongoing medication and conditions you have.
Answer

Question
When should I take Prulitop 2?
Prulitop 2 can be taken at any time of the day. Normally, it is taken orally with or without food once daily. The exact dosage of this medication is to be decided by your prescribing physician. Usually, it is taken as 2 milligrams per day.
Answer

Question
Is Prulitop 2 safe in pregnancy?
No, Prulitop 2 is not safe to be taken during pregnancy. There are few reported cases of spontaneous abortion that have been noted when given in pregnant women. There is little evidence of use of Prulitop 2 in pregnant women. Therefore, its use during pregnancy should be avoided. It is important to consult your doctor before starting this medication.
Answer

Question
Can Prulitop 2 cause gastroparesis?
Prulitop 2 has been proven to be beneficial in cases of gastroparesis and constipation. Gastroparesis is a condition where there is reduced movement of the gut that leads to delayed emptying of the stomach and constipation. Generally, this occurs in conditions like diabetes or after surgery.
Answer
Question
What if you forget to take Prulitop Tablet?
If you miss a dose of Prulitop 2, skip it and continue with your normal schedule. Do not double the dose.
Answer

Prulitop 2 Tablet Reviews

Prulitop 2 is a prescription medicine used in the treatment of constipation. It increases the release of certain chemical that improves the movement of food inside the intestine and helps to increase gastric emptying of both liquid and solid.

Prulitop 2 is taken with or without food in a dose and duration as advised by the doctor. The dose you're given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, nausea, abdominal pain, decreased appetite, dizziness, and dyspepsia. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should avoid this medicine if you are suffering from bleeding ulcers of the stomach. Consult with your doctor if are pregnant or breastfeeding.

How Prulitop 2 Tablet Works

Prulitop 2 is a selective 5-HT4 receptor agonist that has high intrinsic activity. It indirectly stimulates the release of acetylcholine, a chemical messenger that increases the motility of the intestine and treats even chronic (long-term) constipation very effectively.

How to Use Prulitop 2 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prulitop 2 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Prulitop 2 Tablet

  • In Treatment of Constipation: Prulitop 2 helps to stimulate bowel movements. It increases the movement of the intestines, this helps empty your bowels and relieve constipation. Emptying of both solid and liquid wastes relieves the pain and discomfort caused due to constipation and improves your quality of life. Eat more high-fiber foods including fruit and vegetables and drink plenty of water to prevent constipation from happening.

Uses of Prulitop 2 Tablet

  • Treatment of Constipation

Prulitop 2 Tablet Side Effects

Item form

Safety Tips

Pregnancy  CONSULT YOUR DOCTOR
Prulitop 2 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving  UNSAFE
Prulitop 2 may cause side effects which could affect your ability to drive.Prulitop 2 may cause dizziness and tiredness, especially on the first day of treatment, and this may have an effect on driving and use of machines.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Prulitop 2. Please consult your doctor.
Kidney  CAUTION
Prulitop 2 should be used with caution in patients with severe kidney disease. Dose adjustment of Prulitop 2 may be needed. Please consult your doctor.
Liver  CAUTION
Prulitop 2 should be used with caution in patients with severe liver disease. Dose adjustment of Prulitop 2 may be needed. Please consult your doctor.Limited information is available on the use of Prulitop 2 in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Breast feeding  CONSULT YOUR DOCTOR
Prulitop 2 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Quick Tips

  • Prulitop 2 helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
  • Inform your doctor if your constipation has not improved even after four weeks of taking this medication.
  • It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
  • It can be taken with or without food, at any time of the day.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1327.
  2. Prucalopride [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2020.
  3. Prucalopride succinate. London, England: Shire Pharmaceuticals Limited; 2009 [revised 27 May 2015].
  4. Prucalopride. Baggot Street Lower Dublin: Shire Pharmaceuticals; 2009 [revised Mar. 2019].

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