Ranomend 500 ER Tablet


Product Info

Prescription required Yes
Marketer Mendcure Life Sciences Pvt Ltd
Active Ingredient Ranolazine (500mg)
Storage Store below 30°C
Chemical ClassAcetanilide & piperazine derivative
Habit FormingNo
Therapeutic ClassCARDIAC
Action ClassLate Sodium channel blocker- angina
User Rating4.4
User Reviews474

FAQ

Question
I started taking Ranomend 500 ER about a week ago. Now I have noticed that my urine has become very dark though I am taking plenty of fluids. Is there anything to worry about?
Urine discoloration could be because of Ranomend 500 ER. You need not worry if you do not have any other symptoms. However, if it still bothers you, you can talk to your doctor who will advise you further.
Answer

Question
In case I accidentally take an excess of Ranomend 500 ER, what will happen?
Excess of Ranomend 500 ER can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking and you can even faint. If you have taken an excess of Ranomend 500 ER by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.
Answer

Question
Is it safe to take Ranomend 500 ER if I am already taking metoprolol?
Yes, it is safe to take the Ranomend 500 ER and Metoprolol together. Ranomend 500 ER has minimal effect on blood pressure in patients with angina.
Answer

Question
I have been taking simvastatin to keep my cholesterol levels in check. Can I take Ranomend 500 ER with it?
It is recommended not to take simvastatin and Ranomend 500 ER together because it may cause simvastatin toxicity which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take, then take it exactly as advised by the doctor.
Answer

Question
I am a diabetic and am taking metformin. My doctor has prescribed Ranomend 500 ER, is it safe to take both together?
If you are taking metformin along with Ranomend 500 ER, you have to be careful since Ranomend 500 ER may increase the levels of metformin in the body which can lead to metformin toxicity. Talk to your doctor who will modify the dose of metformin.
Answer

Question
What are the serious side effects of Ranomend 500 ER?
Ranomend 500 ER may cause changes in the electrical activity of the heart which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint, lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Ranomend 500 ER may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.
Answer
Question
What if you forget to take Ranomend Tablet ER?
If you miss a dose of Ranomend 500 ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Ranomend 500 ER Tablet Reviews

Ranomend 500 ER is used for the management of angina (heart-related chest pain). It helps to prevent new attacks of angina but does not stop an acute attack, once started. It relieves chest pain by making the heart work more efficiently.

Ranomend 500 ER should be taken in the dose as advised by your doctor, at the same time each day. It should be taken with food to avoid stomach upset. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm. If you stop taking it, your chest pain may come back.

You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress. Some common side effects of this medicine include nausea, vomiting, headache, dizziness, constipation, and weakness. Talk to your doctor if these bother you or do not go away.

Ranomend 500 ER may not suitable for some people. Tell your doctor if you are suffering from any liver or kidney problems. Also let your doctor know all other medications you are using as some may affect, or be affected by this medicine. This medicine is not usually recommended during pregnancy or breastfeeding.

How Ranomend 500 ER Tablet Works

Ranomend 500 ER is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.

How to Use Ranomend 500 ER Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ranomend 500 ER is to be taken with food.

Benefits of Ranomend 500 ER Tablet

  • In Treatment of Angina (heart-related chest pain): Ranomend 500 ER reduces the oxygen requirement of the heart and relaxes the heart muscles. It makes sure that your heart is able to perform its functions in the amount of oxygen supply available without causing stress on heart muscles. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Uses of Ranomend 500 ER Tablet

  • Treatment of Angina (heart-related chest pain)

Ranomend 500 ER Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Ranomend 500 ER should be used with caution in patients with kidney disease. Dose adjustment of Ranomend 500 ER may be needed. Please consult your doctor.Use of Ranomend 500 ER is not recommended in patients with severe kidney disease.
Liver  CAUTION
Ranomend 500 ER should be used with caution in patients with liver disease. Dose adjustment of Ranomend 500 ER may be needed. Please consult your doctor.Use of Ranomend 500 ER is not recommended in patients with moderate to severe liver disease.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ranomend 500 ER. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Ranomend 500 ER alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Breast feeding  CONSULT YOUR DOCTOR
Ranomend 500 ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy  CONSULT YOUR DOCTOR
Ranomend 500 ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Quick Tips

  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • It improves HbA1c and blood sugar levels in diabetes patients.
  • Notify your doctor if you are taking any other medications along with Ranomend 500 ER
  • It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.
  • It should be taken with food to avoid stomach upset.

References

  1. Ranolazine. Foster City, California: Gilead Sciences, Inc.; 2013.
  2. Ranolazine. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 22 Nov. 2018].
  3. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 56
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1200.
  5. Ranolazine Sustained Release Tablets [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2019.
  6. Central Drugs Standard Control Organisation (CDSCO).

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