Refract 25mg Tablet


Product Info

Prescription required Yes
Marketer Crescent Therapeutics Ltd
Active Ingredient Clozapine (25mg)
Storage Store below 30°C
Chemical ClassDibenzodiazepine Derivative
Habit FormingNo
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
User Rating4.9
User Reviews744

FAQ

Question
Does Refract 25mg help with anxiety?
Yes, Refract 25mg helps calm the mind and decreases the level of anxiety and aggressive behavior in patients with Schizophrenia.
Answer

Question
I am experiencing a change in my taste after the start of the treatment with Refract 25mg. Any tips to reduce it?
A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.
Answer

Question
Is Refract 25mg addictive?
No, Refract 25mg is not addictive in nature. No habit-forming potential has been seen with its use. However, always follow your doctor's advice regarding the duration of its use.
Answer

Question
Can Refract 25mg cause dizziness?
Yes. Refract 25mg can cause dizziness by reducing blood pressure. If this happens to you, you should sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while traveling.
Answer

Question
How long does it take for Refract 25mg to work?
Like many medicines, Refract 25mg does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.
Answer

Question
I am having trouble remembering to take my medications. Is there anything I can do to help me remember?
In order to avoid missing a dose, use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member a friend to remind you or check in with you to be sure you are taking your medication.
Answer

Question
Why do I have to have regular blood tests while I am taking Refract 25mg?
Refract 25mg is known to cause a rare but serious side effect called “agranulocytosis”. This side effect occurs in less than 1 out of every 100 people who take this medicine. This side effect can result in a decrease in the number of white blood cells (infection-fighting cells) in your body. Without enough white blood cells, your body may not be able to. In order to prevent this, your doctor may prescribe you a blood test to check your white blood cell count.
Answer

Question
Can I drink alcohol while taking Refract 25mg?
It is recommended that people taking this medicine should not drink alcohol. This is because Refract 25mg is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.
Answer

Question
What happens if I stop taking Refract 25mg?
It is advisable not to stop taking this medicine without talking to your doctor, since it may worsen your symptoms. Your doctor will probably want to decrease your dose gradually.
Answer

Question
Why has Refract 25mg been prescribed?
Refract 25mg is an antipsychotic drug used to treat manic episodes and Schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning. It is also used to reduce the risk of suicidal behavior in people with Schizophrenia.
Answer

Question
When should I see my doctor?
Seek immediate medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction, pain or burning when you urinate, or vaginal itching or discharge.
Answer
Question
What if you forget to take Refract Tablet?
If you miss a dose of Refract 25mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Refract 25mg Tablet Reviews

Refract 25mg is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave).

Refract 25mg may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include hypotension, dry mouth, headache, increased sweating, visual disturbance, and decreased blood pressure. Please consult your doctor if these side effects do not get better or worse.

Before taking this medicine it is important to inform your doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), heart disease, diabetes, Parkinson’s disease, dementia, fits (epilepsy), difficulty in swallowing (dysphagia), or liver problems.

How Refract 25mg Tablet Works

Refract 25mg is an atypical antipsychotics. It works by modulating the action of certain chemical messengers in the brain that affects thoughts.

How to Use Refract 25mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Refract 25mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Refract 25mg Tablet

  • In Schizophrenia: Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Refract 25mg helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Uses of Refract 25mg Tablet

  • Schizophrenia

Refract 25mg Tablet Side Effects

Item form

Safety Tips

Driving  UNSAFE
Refract 25mg may cause side effects which could affect your ability to drive.
Breast feeding  CONSULT YOUR DOCTOR
Refract 25mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Refract 25mg.
Kidney  CAUTION
Refract 25mg should be used with caution in patients with kidney disease. Dose adjustment of Refract 25mg may be needed. Please consult your doctor.
Liver  CAUTION
Refract 25mg should be used with caution in patients with liver disease. Dose adjustment of Refract 25mg may be needed. Please consult your doctor.
Pregnancy  SAFE IF PRESCRIBED
Refract 25mg is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Quick Tips

  • Take it with or without food, preferably at the same time everyday.
  • It may cause low blood pressure and dehydration. Drink plenty of fluids and rise slowly from a sitting or lying position.
  • It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
  • It can cause dizziness and sleepiness. Be cautious while driving or doing anything that requires concentration.
  • Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Refract 25mg helps treat schizophrenia in people for whom other medicines are ineffective or not tolerated.
  • Do not stop taking Refract 25mg without talking  to your doctor first as it may cause worsening of symptoms.

References

  1. Clozapine. East Hanover, New Jersey: Novartis Pharmaceuticals; 2004.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 308-309.
  3. Clozapine. Potters Bar, Hertfordshire: Mylan Products Limited; 1989 [revised Dec. 2018].
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
  5. Clozapine [Patient Information Leaflet]. Ahmedabad, Gjjarat: Torrent Pharmaceuticals Ltd.; 2014.
  6. Central Drugs Standard Control Organisation (CDSCO).
  7. Stahl SM, editor. Clozapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 153-59.

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