Regest 40 Tablet


Product Info

Prescription required Yes
Marketer Renace Pharmaceuticals
Active Ingredient Megestrol (40mg)
Storage Store below 30°C
Chemical ClassProgesterone Congeners
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
Action ClassProgestins (First generation)
User Rating4.9
User Reviews418

FAQ

Question
Does Regest 40 prevent pregnancy?
No, Regest 40 does not prevent pregnancy. It may disrupt your normal menstrual cycle but does not prevent pregnancy. Hence, you should use a reliable method of birth control to prevent pregnancy. Check with your doctor in case you are not sure or have any doubts.
Answer

Question
What is Regest 40? What is it used for?
Regest 40 contains Megestrol, which is similar to the naturally produced hormone progesterone. The medicine is used in treatment hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.
Answer

Question
Is Regest 40 acetate safe to be taken during pregnancy?
No, you should not take Regest 40 if you are pregnant or are planning a pregnancy. However, if you become pregnant while taking Regest 40, immediately contact your doctor as Regest 40 may cause harm to your unborn baby. It is important to inform the doctor because it may cause abnormalities of sex organs in male and female babies if it is taken during first 3 months of pregnancy. Usually, the doctor may suggest a pregnancy test before starting your treatment with Regest 40.
Answer

Question
Is Regest 40 a chemo medicine?
No, Regest 40 is not a chemo medicine. It is a man-made version of the progesterone hormone. It is helpful in the treatment of breast cancer and endometrial cancer (cancer of the uterus). It works by modifying the female hormones involved in cancer growth.
Answer

Question
Does Regest 40 make you gain weight?
Yes, Regest 40 may cause weight gain as a very common side effect. Weight gain could be due to an increase in appetite which leads to an overall increase in fat and body cell mass. Consult your doctor if you experience excessive weight gain. It is commonly used to treat malnutrition, loss of appetite and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). However, it is not intended for preventive use to avoid weight loss.
Answer

Question
What is Regest 40 and what is it used for?
Regest 40 contains a medicine called Megestrol which is similar to the hormone progesterone, that naturally occurs in your body. It is used in hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.
Answer

Question
Is Regest 40 used for hot flashes?
Use of Regest 40 in hot flashes is not approved. Always consult your doctor before using Regest 40. Usually, estrogen in women and androgen in men are used for the treatment of hot flashes but these hormones cannot be used in females with breast cancer and males with prostate cancer.
Answer

Question
Does Regest 40 stop periods?
No, Regest 40 does not stop periods. However, it may interfere with your normal menstrual cycle. It may cause break-through bleeding and therefore has limited use in HIV infected women. Consult your doctor in case you experience breakthrough bleeding during the treatment with Regest 40.
Answer

Question
When should I take Regest 40?
You can take Regest 40 at any time of the day. However, you should take it exactly as prescribed by your doctor. Swallow it whole with a glass of water. It can be taken with or without food, preferably at the same time each day since this helps you to remember taking it. Check with your doctor if you are not sure.
Answer

Question
Does Regest 40 need to be refrigerated?
No, there is no need to refrigerate Regest 40. However, this medicine should not be stored above 25°C. It should be stored in original packaging to protect from moisture.
Answer

Regest 40 Tablet Reviews

Regest 40 is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV.

Regest 40 should be taken as your doctor advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include weight gain, increase in appetite, shortness of breath, hot flushes (warm face and neck), high blood pressure, and constipation. Most of these are temporary, and go away as soon as the body adjusts to the treatment. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine. Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine.

How Regest 40 Tablet Works

Regest 40 is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.

How to Use Regest 40 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Regest 40 may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Regest 40 Tablet

  • In Endometrial cancer: Regest 40 is a synthetic hormone which replicates the effect of a natural female hormone called progesterone. It relieves the symptoms of endometrial cancer (a type of cancer that develops in the lining of the womb) such as, abnormal vaginal bleeding, lower back pain, pain during sex, etc. It interferes with the production and working of those hormones in the body that are essential for the growth and spread of endometrial cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.
  • In Breast cancer: Regest 40 relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.

Uses of Regest 40 Tablet

  • Breast cancer
  • Endometrial cancer

Regest 40 Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Regest 40 should be used with caution in patients with severe kidney disease. Dose adjustment of Regest 40 may be needed. Please consult your doctor.
Liver  CAUTION
Regest 40 should be used with caution in patients with severe liver disease. Dose adjustment of Regest 40 may be needed. Please consult your doctor.
Pregnancy  UNSAFE
Regest 40 is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Regest 40. Please consult your doctor.
Driving  SAFE
Regest 40 does not usually affect your ability to drive.
Breast feeding  CONSULT YOUR DOCTOR
Regest 40 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Quick Tips

  • Regest 40 is used to treat women with certain hormone-dependent cancers such as breast cancer and endometrial cancer.
  • Do not take Regest 40 if you are pregnant or breastfeeding.
  • Do not stop taking the medicine suddenly without talking to your doctor first.
  • You may have to take it for atleast 2 months before you notice any changes in your appetite.
  • It may also be used for treating appetite and weight loss in people with advanced cancer or AIDS.
  • Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine.
  • Inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein.

References

  1. Central Drugs Standard Control Organisation (CDSCO).
  2. Megestrol. Spring Valley, New York: Par Pharmaceutical Companies, Inc.; 1993 [revised May 2013].
  3. Medsacpe. Megestrol.
  4. Megestrol acetate [Drug Label]. Princeton, New Jersey: Bristol-Myers Squibb Company; 2012.

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