Salazed 500 Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Jagsonpal Pharmaceuticals Ltd
Active Ingredient	Sulfasalazine (500mg)
Storage	Store below 30°C
Chemical Class	Aminosalicylic Acids Derivative
Habit Forming	No
Therapeutic Class	GASTRO INTESTINAL
Action Class	Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics
User Rating	4.2
User Reviews	301

FAQ

Is Salazed 500 a steroid or a painkiller?

Salazed 500 is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn's disease in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).

Can I take azathioprine along with Salazed 500?

You should avoid using Salazed 500 with azathioprine since there are chances of decrease in blood cell count, which can be a serious side effect.

I have been prescribed Salazed 500 for rheumatoid arthritis. When can I expect the pain in joints to be better?

Salazed 500 does not work right away. It takes about 6 to 12 weeks to deliver the full effect.You may start feeling better in 4 weeks after starting Salazed 500, but it can vary from person to person and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.

Does the use of Salazed 500 for the treatment of arthritis affect the kidney function?

Though it is uncommon, Salazed 500 may affect your kidney function. Therefore, it is important that your kidney function remains normal before you start taking Salazed 500. If during treatment with Salazed 500 your kidney functions become abnormal, you should consult your doctor.

Can Salazed 500 affect my fertility?

Decreased sperm count and infertility have been reported in some males. These may disappear once Salazed 500 is discontinued.

Do I need to get any blood tests done while on Salazed 500 therapy?

Your doctor will advise you blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver known as enzymes (liver function tests) and urine for protein and blood before you start treatment and at regular intervals.

What is Salazed 500 and what is it used for?

Salazed 500 belongs to a group of medicines called aminosalicylates. It is an anti-inflammatory disease and is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis and Crohn’s disease. In rheumatoid arthritis, it helps prevent damage to the joints and works slowly to reduce swelling and stiffness in your joints.

For how long do I need to take Salazed 500?

If you are able to tolerate Salazed 500 which means the side effects do not bother you, then you have to continue Salazed 500 till the disease remains in remission. It is better to take Salazed 500 for the prescribed period.

What if you forget to take Salazed Tablet?

If you miss a dose of Salazed 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Salazed 500 Tablet Reviews

Salazed 500 is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease).

Salazed 500 is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones.

Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

How Salazed 500 Tablet Works

Salazed 500 is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

How to Use Salazed 500 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Salazed 500 is to be taken with food.

Benefits of Salazed 500 Tablet

In Treatment of Rheumatoid arthritis: Salazed 500 helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have any bothersome side effects after taking this medicine.
In Treatment of Ulcerative colitis: Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.
In Treatment of Ankylosing spondylitis: Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Salazed 500 helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.
In Treatment of Crohn’s disease: Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Salazed 500 helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.
In Treatment of Psoriatic arthritis: Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects some individuals with psoriasis, causing joint pain, swelling, and stiffness alongside skin symptoms. Salazed 500 has anti-inflammatory properties that help reduce joint pain, swelling, and stiffness. This medicine can also slow down the progression of joint damage associated with PsA. Additionally, it can help improve skin symptoms in individuals with both psoriasis and arthritis.

Uses of Salazed 500 Tablet

Treatment of Ankylosing spondylitis
Treatment of Rheumatoid arthritis
Treatment of Psoriatic arthritis
Treatment of Ulcerative colitis
Treatment of Crohn’s disease

Salazed 500 Tablet Side Effects

Safety Tips

Liver ^UNSAFE

Salazed 500 is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Kidney ^CAUTION

Salazed 500 should be used with caution in patients with kidney disease. Dose adjustment of Salazed 500 may be needed. Please consult your doctor.Regular monitoring of kidney function tests is advisable while you are taking this medicine.

Breast feeding ^{CONSULT YOUR DOCTOR}

Salazed 500 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving ^SAFE

Salazed 500 does not usually affect your ability to drive.

Pregnancy ^{SAFE IF PRESCRIBED}

Salazed 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Alcohol ^UNSAFE

It is unsafe to consume alcohol with Salazed 500.

Quick Tips

Do not stop taking the medication suddenly without talking to your doctor.
It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
Take it with food to avoid an upset stomach.
It may take 6-8 weeks for Salazed 500 to work. Keep taking it as prescribed.
Do not take Salazed 500 if you are allergic to sulfa drugs or aspirin.
Drink plenty of fluids while taking Salazed 500 in order to avoid kidney problems such as kidney stones.
Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor.

References

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Sulfasalazine. Uppsala, Sweden: Recipharm, Uppsala; 2018.
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 632-33.
Oxford Radcliffe Hospitals: NHS Trust. Sulfasalazine.
Sulfasalazine. Sandwich, Kent: Pfizer Limited; 2010 [revised Feb. 2014].
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198.
National Health Service. Sulfasalazine.
Sulfasalazine. New York, New York: Pharmacia & Upjohn Co.; 2014.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1295-97.