Sistal AP Tablet


Product Info

Prescription required Yes
Marketer BestoChem Formulations India Ltd
Active Ingredient Aceclofenac (100mg) + Paracetamol (325mg) + Trypsin Chymotrypsin (50000AU)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassPAIN ANALGESICS
User Rating4.1
User Reviews690

FAQ

Question
What if I forget to take Sistal AP?
If you forget to take the scheduled dose of Sistal AP and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, consult your doctor about how to manage a situation like this.
Answer

Question
Can the use of Sistal AP cause dizziness?
Yes, the use of Sistal AP can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Answer

Question
Can I stop taking Sistal AP when my pain is relieved?
Sistal AP is usually used for short term and can be discontinued when your pain is relieved. However, Sistal AP should be continued if your doctor has advised you to do so.
Answer

Question
How long will Sistal AP take to act?
It may take about an hour to see the initial benefit of pain relief after taking Sistal AP.
Answer

Question
Can the use of Sistal AP cause damage to kidneys?
Yes, long-term use of Sistal AP can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage due to long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.
Answer

Question
Can the use of Sistal AP cause damage to liver?
Sistal AP contains Paracetamol. This medicine is known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.
Answer

Question
Will a higher than the recommended dose of Sistal AP be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Answer

Question
Are there any specific contraindications associated with the use of Sistal AP?
The use of Sistal AP is considered to be harmful for patients with known allergy to any of the component or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.
Answer

Question
Can I get addicted to Sistal AP?
No, there is no report of any patient getting addicted to Sistal AP.
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Question
What is Sistal AP?
Sistal AP is a combination of four medicines: Aceclofenac, Paracetamol, Trypsin and Chymotrypsin. This medicine helps in decreasing pain and swelling. It lowers the levels of chemical substances in the body that causes pain and swelling.
Answer
Question
What if you forget to take Sistal AP?
If you miss a dose of Sistal AP, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Sistal AP Tablet Reviews

Sistal AP is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Sistal AP should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, heartburn, stomach pain, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

How Sistal AP Tablet Works

Sistal AP is a combination of three medicines: Aceclofenac, Paracetamol and Trypsin Chymotrypsin, which relieves pain. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Trypsin Chymotrypsin is a combination of enzymes which break down proteins into smaller fragments, thereby making them available for absorption into the blood. Once absorbed, they increase blood supply in the affected area and reduce swelling.

How to Use Sistal AP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sistal AP is to be taken with food.

Benefits of Sistal AP Tablet

  • In Pain relief: Sistal AP relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also helps to manage short term symptoms such as muscle and back pain, toothache, or pain in the ear and throat if taken when the first sign of pain occurs. It works by reducing substances in the body that causes pain and swelling. Sistal AP also reduces fever associated with various painful conditions within 1-2 hour of taking a dose.

Uses of Sistal AP Tablet

  • Pain relief

Sistal AP Tablet Side Effects

Item form

Safety Tips

Liver  CAUTION
Sistal AP should be used with caution in patients with liver disease. Dose adjustment of Sistal AP may be needed. Please consult your doctor.However, the use of Sistal AP is not recommended in patients with severe liver disease and active liver disease.
Driving  UNSAFE
Sistal AP may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Sistal AP.
Pregnancy  CONSULT YOUR DOCTOR
Sistal AP may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Kidney  CAUTION
Sistal AP should be used with caution in patients with kidney disease. Dose adjustment of Sistal AP may be needed. Please consult your doctor.Use of Sistal AP is not recommended in patients with severe kidney disease.
Breast feeding  CONSULT YOUR DOCTOR
Information regarding the use of Sistal AP during breastfeeding is not available. Please consult your doctor.

Quick Tips

  • You have been prescribed this combination medicine for relieving pain and inflammation.
  • Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first. 
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Take it with food to avoid getting an upset stomach.
  • Avoid consuming alcohol when taking Sistal AP as it may cause excessive drowsiness and increase the risk of liver damage.

References

  1. Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. Adv Ther. 2018;35(1):31-42.
  2. Trypsin-Chymotrypsin with Paracetamol and Aceclofenac Tablets [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals; 2020.

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