Sivel 400mg Tablet

 Reviews  How to Use  Benefits  Uses  Side Effects

Product Info

Prescription required Yes
Marketer Sanzyme Ltd
Active Ingredient Sevelamer (400mg)
Storage Store below 30°C
Chemical ClassEpoxide
Habit FormingNo
Therapeutic ClassBLOOD RELATED
Action ClassPhosphorous binder
User Rating4.9
User Reviews312
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FAQ

Question
Can I take ciprofloxacin while I am taking Sivel 400mg?
Ciprofloxacin may interfere with the working of Sivel 400mg and therefore it should not be taken at the same time as Sivel 400mg. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sivel 400mg should be maintained.
Answer
Question
Why is it important for me to take Sivel 400mg?
It is important to take Sivel 400mg as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sivel 400mg, as it binds phosphate from food in the digestive tract.
Answer
Question
Can Sivel 400mg be crushed?
No, you should not crush, chew, or break Sivel 400mg into pieces. You should swallow it as a whole with water.
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Question
Do I need to have any tests while taking Sivel 400mg?
Yes, serum phosphate levels should be monitored regularly while you are taking Sivel 400mg. Also, the use of Sivel 400mg may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.
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Question
Does Sivel 400mg cause constipation?
A common side effect of Sivel 400mg is constipation, though it does not occur in everyone. The other common side effects of the stomach and intestine include diarrhea, indigestion, flatulence, and pain in the abdomen. Immediately consult your doctor if these side effects become severe and disturb you.
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Question
How long do I need to take Sivel 400mg?
Continue taking Sivel 400mg as long as recommended by your doctor. Sivel 400mg lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it lifelong, as stopping Sivel 400mg may increase your phosphate levels.
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Question
Is Sivel 400mg taken with food?
Yes, Sivel 400mg can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sivel 400mg works by binding to phosphate from food. Take it exactly as advised by your doctor.
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Question
Who should not take Sivel 400mg?
Patients who are allergic to Sivel 400mg and who have low levels of phosphate in blood should avoid taking Sivel 400mg. Additionally, patients having intestinal obstruction should also avoid using Sivel 400mg.
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Question
What if you forget to take Sivel Tablet?
If you miss a dose of Sivel 400mg, skip it and continue with your normal schedule. Do not double the dose.
Answer

Sivel 400mg Tablet Reviews

Sivel 400mg is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood.

Sivel 400mg should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine.

Sivel 400mg may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.

How Sivel 400mg Tablet Works

Sivel 400mg inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood.

How to Use Sivel 400mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sivel 400mg is to be taken with food.

Uses of Sivel 400mg Tablet

  • High phosphate levels in blood

Sivel 400mg Tablet Side Effects

Item form

Safety Tips

Kidney  SAFE IF PRESCRIBED
Sivel 400mg is safe to use in patients with kidney disease. No dose adjustment of Sivel 400mg is recommended.However, regular monitoring of calcium levels is advisable in these patients.
Driving  CONSULT YOUR DOCTOR
It is not known whether Sivel 400mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Breast feeding  SAFE IF PRESCRIBED
Sivel 400mg is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sivel 400mg. Please consult your doctor.
Pregnancy  CONSULT YOUR DOCTOR
Sivel 400mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Liver  SAFE IF PRESCRIBED
Sivel 400mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sivel 400mg may not be needed in these patients. Please consult your doctor.

Quick Tips

  • You must take it with food and stick to the diet prescribed by your doctor.
  • Avoid taking any other medicine 1 hour before or 3 hours after taking Sivel 400mg.
  • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
  • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
  • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
  • Avoid taking any other medicine 1 hour before or 3 hours after taking Sivel 400mg.
  • Sivel 400mg is used to control blood phosphate level in patients that are on dialysis treatment.
  • You must take it with food and stick to the diet prescribed by your doctor.
  • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
  • Sivel 400mg is used to control blood phosphate level in patients that are on dialysis treatment.

References

  1. Central Drugs Standard Control Organisation (CDSCO).
  2. Medscape. Sevelamer.
  3. Sevelamer hydrochloride. Guildford, Surrey: SANOFI; 2000 [revised 20 Dec. 2018].
  4. Sevelamer Carbonate [Product Information]. Ahmedabad, Gujarat: La Renon.
  5. National Center for Biotechnology Information. PubChem Compound Summary for , Sevelamer.
  6. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1259.
  7. Sevelamer. Cambridge, USA: Genzyme Corporation; 1998.

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