Syncapone 50 Tablet


Product Info

Prescription required Yes
Marketer Sun Pharmaceutical Industries Ltd
Active Ingredient Levodopa (50mg) + Carbidopa (12.5mg) + Entacapone (200mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassNEURO CNS
User Rating4.8
User Reviews599

FAQ

Question
What if you forget to take Syncapone Tablet?
If you miss a dose of Syncapone 50, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Syncapone 50 Tablet Reviews

Syncapone 50 is a prescription medicine used in the treatment of Parkinson's disease. This medicine helps to reduce excessive shaking by slowing down the body movements. It works by increasing the amount of chemical messenger that is needed to control abnormal movements.

Syncapone 50 is taken with or without food, but better to avoid high protein meal and dairy products. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it can result in harmful effects.

This medicine may cause side effects like nausea, diarrhea, vomiting, constipation, discoloration of urine, and dryness in the mouth. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.  It is common to have diarrhea with this medicine, so drink plenty of fluids and watch for weight loss.

Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

How Syncapone 50 Tablet Works

Syncapone 50 is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.

How to Use Syncapone 50 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Syncapone 50 may be taken with or without food, but it is better to take it at a fixed time.Avoid Syncapone 50 with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

Benefits of Syncapone 50 Tablet

  • In Parkinson's disease: Syncapone 50 is a medicine that helps relieve symptoms of Parkinson's disease such as tremors, muscle stiffness and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

Uses of Syncapone 50 Tablet

  • Parkinson's disease

Syncapone 50 Tablet Side Effects

Item form

Safety Tips

Alcohol  UNSAFE
It is unsafe to consume alcohol with Syncapone 50.
Driving  UNSAFE
Syncapone 50 may cause side effects which could affect your ability to drive.Caution is advised when driving or operating machinery.
Liver  CAUTION
Syncapone 50 should be used with caution in patients with liver disease. Dose adjustment of Syncapone 50 may be needed. Please consult your doctor.
Breast feeding  CONSULT YOUR DOCTOR
Syncapone 50 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pregnancy  CONSULT YOUR DOCTOR
Syncapone 50 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Kidney  CAUTION
Syncapone 50 should be used with caution in patients with severe kidney disease. Dose adjustment of Syncapone 50 may be needed. Please consult your doctor.

Quick Tips

  • Do not stop taking the medication suddenly without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating and confusion.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking this medicine as that can reduce the amount of medication absorbed by your body. 
  • It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Talk to your doctor in case you develop hallucinations or notice other changes in your behavior.
  • You have been prescribed Syncapone 50 to treat your symptoms of parkinson's disease.

References

  1. European Medicine Agency. Levodopa+Carbidopa+Entacapone Sandoz; 2014.
  2. Carbidopa, levodopa and entacapone [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2014.
  3. Levodopa+Carbidopa+Entacapone. Espoo, Finland: Orion Corporation; 2010.

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