Tbzide Tablet
Product Info
| Prescription required | Yes |
| Marketer | Biochem Pharmaceutical Industries |
| Active Ingredient | Pyrazinamide (NA) |
| Storage | Store below 30°C |
| Chemical Class | Nicotinic acid derivatives |
| Habit Forming | No |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Mycobacterial fatty acid synthase |
| User Rating | 4.4 |
| User Reviews | 332 |
FAQ
How does Tbzide cause hyperuricemia and gout?
Following oral intake of Tbzide, it gets converted in the body to pyrazinoic acid (active chemical form of Tbzide). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).
Is Tbzide bactericidal?
Tbzide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases
How does Tbzide work/treat tuberculosis?
Tbzide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Tbzide is not known
What is Tbzide and what is it used for?
Tbzide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis
What if you forget to take Tbzide?
If you miss a dose of Tbzide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Tbzide Tablet Reviews
Tbzide is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
Tbzide is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification.
Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Tbzide is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.
Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification.
Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.
How Tbzide Tablet Works
Tbzide is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.
How to Use Tbzide Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tbzide may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Tbzide Tablet
- In Tuberculosis (TB): Tbzide is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Uses of Tbzide Tablet
- Tuberculosis (TB)
Tbzide Tablet Side Effects
Safety Tips
Pregnancy
CONSULT YOUR DOCTOR
Tbzide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Kidney
CAUTION
Tbzide should be used with caution in patients with severe kidney disease. Dose adjustment of Tbzide may be needed. Please consult your doctor.Kidney function tests are advised before you start taking this medicine.
Breast feeding
SAFE IF PRESCRIBED
Tbzide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Liver
CAUTION
Tbzide should be used with caution in patients with liver disease. Dose adjustment of Tbzide may be needed. Please consult your doctor.Regular monitoring of liver function tests is advised before and after the start of the treatment.
Driving
CONSULT YOUR DOCTOR
It is not known whether Tbzide alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Tbzide. Please consult your doctor.
Quick Tips
- Avoid drinking alcohol while taking Tbzide as this may increase the risk of side effects on the liver.
- Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
- Tbzide along with other medications effectively treats tuberculosis.
- Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Tbzide as it may make hormonal contraceptives such as the pill less effective.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1171-72.
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1554-555.
- Central Drugs Standard Control Organisation (CDSCO).
- Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 827.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198
- Drugs.com. Pyrazinamide.