Tendc-M 500 Tablet ER


Product Info

Prescription required Yes
Marketer FDC Ltd
Active Ingredient Metformin (500mg) + Teneligliptin (20mg)
Storage Store below 30°C
Habit FormingNo
Therapeutic ClassANTI DIABETIC
User Rating4.2
User Reviews646

FAQ

Question
Can the use of Tendc-M 500 cause lactic acidosis?
Yes, the use of Tendc-M 500 can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Tendc-M 500 and immediately consult your doctor.
Answer

Question
Can the use of Tendc-M 500 lead to Vitamin B12 deficiency?
Yes, the use of Tendc-M 500 can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Deficiency of B12 may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.
Answer

Question
What is the storage condition for the Tendc-M 500?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Answer

Question
Can the use of Tendc-M 500 lead to hypoglycemia?
The use of Tendc-M 500 does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.
Answer

Question
Are there any specific contraindications associated with the use of Tendc-M 500?
The use of Tendc-M 500 should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.
Answer

Question
Is it safe to use Tendc-M 500?
Yes, it is safe to use Tendc-M 500 if you take it for the prescribed duration and according to the dosage advised by the doctor. However, despite taking the prescribed dosage you might experience common side effects like nausea, diarrhea, vomiting, stomach upset, headache, nasal congestion, sore throat, respiratory tract infection and hypoglycemia (low blood sugar level). Hypoglycemia is relatively common in patients who are taking Tendc-M 500 in combination with insulin or Sulfonylurea. Inform your doctor if you experience any persistent problem while taking this medicine.
Answer

Question
Can the use of Tendc-M 500 cause nausea and vomiting?
Yes, the use of Tendc-M 500 can cause nausea and vomiting. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.
Answer
Question
What if you forget to take Tendc-M Tablet ER?
If you miss a dose of Tendc-M 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Tendc-M 500 Tablet ER Reviews

Tendc-M 500 is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.

Tendc-M 500 can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, and headache. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

How Tendc-M 500 Tablet ER Works

Tendc-M 500 is a combination of two antidiabetic medicines:.

How to Use Tendc-M 500 Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tendc-M 500 is to be taken with food.

Benefits of Tendc-M 500 Tablet ER

  • In Treatment of Type 2 diabetes mellitus: Tendc-M 500 is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

Uses of Tendc-M 500 Tablet ER

  • Treatment of Type 2 diabetes mellitus

Tendc-M 500 Tablet ER Side Effects

Item form

Safety Tips

Breast feeding  CONSULT YOUR DOCTOR
Tendc-M 500 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Tendc-M 500.
Pregnancy  CONSULT YOUR DOCTOR
Tendc-M 500 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Tendc-M 500 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Liver  UNSAFE
Tendc-M 500 is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Kidney  CAUTION
Tendc-M 500 should be used with caution in patients with kidney disease. Dose adjustment of Tendc-M 500 may be needed. Please consult your doctor.Use of Tendc-M 500 is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Quick Tips

  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Tendc-M 500 may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Monitor your blood sugar level regularly while you are taking this medicine.
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar.
  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.

References

  1. Teneligliptin and Metformin Hydrochloride ER [Patient Information Sheet]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2016.
  2. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003.
  3. Teneligliptin and Metformin hydrochloride [Product information] Pune, India: Centaur Pharma Ltd.; 2018.
  4. Teneligliptin and Metformin hydrochloride [Packaging information] Pune, India: Centaur Pharma Ltd.
  5. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company.
  6. Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95.
  7. Teneligliptin and Metformin hydrochloride [Product Monograph] Mumbai, Maharashtra: Panacea Biotec Limited; 2019.

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