Tipanat 8.19mg/20mg Tablet


Product Info

Prescription required Yes
Marketer Natco Pharma Ltd
Active Ingredient Tipiracil (8.19mg) + Trifluridine (20mg)
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
User Rating4.6
User Reviews622

FAQ

Question
Can Tipanat 8.19mg/20mg be taken during pregnancy?
This treatment may harm a baby developing in the womb. It is important not to conceive or father a child while you are on treatment with Tipanat 8.19mg/20mg and for at least 6 months after its final dose. Talk to your doctor about effective contraception before starting the treatment.
Answer

Question
Should I avoid any food and drinks while taking Tipanat 8.19mg/20mg?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent dehydratation, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.
Answer

Question
Can I breastfeed while taking Tipanat 8.19mg/20mg?
No, it is advisable to avoid breastfeeding during the treatment with Tipanat 8.19mg/20mg and for 1 day following its final dose.
Answer

Question
How will you know that Tipanat 8.19mg/20mg is working?
Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
Answer

Question
How to cope with tiredness and weakness after starting the treatment?
Various things can help you reduce tiredness and cope with it, for example, gentle exercise. However, always consult your doctor before doing any kind of exercise.
Answer

Question
How to get relief from diarrhea while on treatment with Tipanat 8.19mg/20mg?
Food items with soluble fiber can help relieve diarrhea as they absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid it. You can also have soups and juices frequently to hydrate yourself.
Answer

Question
What precautions should I take to reduce the chances of getting infected during the treatment with Tipanat 8.19mg/20mg?
Since Tipanat 8.19mg/20mg lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection. In order to prevent this, avoid people who have infections. Check with your doctor immediately if you think you may have been infected, or if you get a fever, chills, or cough.
Answer

Question
Why am I experiencing bleeding from my gums after brushing my teeth?
You may experience bleeding from gums due to a drop in the number of platelets (blood cells) in your blood. These blood cells help the blood clot when we bruise ourselves.
Answer
Question
What if you forget to take Tipanat Tablet?
If you miss a dose of Tipanat 8.19mg/20mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Answer

Tipanat 8.19mg/20mg Tablet Reviews

Tipanat 8.19mg/20mg is a combination of two medicines that treat cancer of the colon and rectum that has spread to other parts of the body (metastasized). It works by stopping or slowing down the growth of cancer cells.

Tipanat 8.19mg/20mg should be taken with food, but try to have it at the same time every day to get the most benefit. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia, neutropenia, fatigue, nausea, thrombocytopenia, decreased appetite, diarrhea, vomiting, and fever. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How Tipanat 8.19mg/20mg Tablet Works

Tipanat 8.19mg/20mg is a combination of two anticancer medications. Trifluridine suppresses DNA synthesis and stops the growth of cancer cells. Tipiracil slows down the degradation of trifluridine in the body.

How to Use Tipanat 8.19mg/20mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tipanat 8.19mg/20mg is to be taken with food.

Benefits of Tipanat 8.19mg/20mg Tablet

  • In Cancer of colon and rectum: Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Tipanat 8.19mg/20mg treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Uses of Tipanat 8.19mg/20mg Tablet

  • Cancer of colon and rectum

Tipanat 8.19mg/20mg Tablet Side Effects

Item form

Safety Tips

Breast feeding  CAUTION
Tipanat 8.19mg/20mg should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Kidney  SAFE IF PRESCRIBED
Tipanat 8.19mg/20mg is safe to use in patients with kidney disease. No dose adjustment of Tipanat 8.19mg/20mg is recommended.
Liver  SAFE IF PRESCRIBED
Tipanat 8.19mg/20mg is safe to use in patients with liver disease. No dose adjustment of Tipanat 8.19mg/20mg is recommended.
Pregnancy  CONSULT YOUR DOCTOR
Tipanat 8.19mg/20mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Alcohol  CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tipanat 8.19mg/20mg. Please consult your doctor.
Driving  CONSULT YOUR DOCTOR
It is not known whether Tipanat 8.19mg/20mg alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Quick Tips

  • Eat foods that may help reduce diarrhea and take adequate rest.
  • You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Avoid the use of antacids within two hours of taking this medicine.
  • To help treat/prevent mouth sores, use a soft toothbrush and rinse your mouth at least 3 times a day with saline water.
  • Use contraceptives, and do not conceive a child (get pregnant) while taking Tipanat 8.19mg/20mg. Barrier methods of contraception, such as condoms should be used during therapy and for 6 months after treatment.
  • Drink plenty of water every 24 hours after the start of the treatment.

References

  1. Trifluridine and Tipiracil [Prescribing Information]. Princeton, NJ: Taiho Oncology, Inc.; 2019.
  2. Trifluridine and Tipiracil [Summary of Product Characteristics]. Gidy, France: Les Laboratoires Servier Industrie; 2016.

Other Medical Preparations