Tolvaptan 30 Tablet
Product Info
| Prescription required | Yes |
| Marketer | Care Formulation Labs Pvt Ltd |
| Active Ingredient | Tolvaptan (30mg) |
| Storage | Store below 30°C |
| Chemical Class | Benzazepine Derivative |
| Habit Forming | No |
| Therapeutic Class | UROLOGY |
| Action Class | Vasopressin antagonist |
| User Rating | 4.4 |
| User Reviews | 779 |
FAQ
What is the most important information I need to be aware of while taking Tolvaptan 30?
Tolvaptan 30 may cause the level of sodium in your blood to increase too quickly. This quick increase in sodium levels [osmotic demyelination syndrome (ODS)] may cause serious nerve damage, which can further cause coma and even death. The symptoms of ODS could be trouble in speaking, trouble in swallowing or a feeling of food or liquid getting stuck while swallowing, drowsiness, confusion, mood changes, fits, trouble controlling body movement (involuntary movement) and weakness in muscles of the arms and legs.
Does Tolvaptan 30 affect the sugar levels in blood?
Yes, Tolvaptan 30 may increase the blood sugar levels. Therefore, patients with diabetes mellitus need to be extra careful while taking Tolvaptan 30 and should keep a check on blood sugar levels regularly.
Can I have grapefruit juice while taking Tolvaptan 30?
No, you should not take grapefruit or grapefruit juice while on Tolvaptan 30. The reason being, grapefruit or grapefruit juice may increase the levels of Tolvaptan 30 in your blood and your sodium levels may rise too quickly.
What will happen if I take excess of Tolvaptan 30?
You may need urgent medical attention. Call your doctor or seek emergency service at a nearby hospital. Symptoms of taking too much Tolvaptan may include thirst, dry and flaky skin, sunken eyes, rapid heartbeat, rapid and shallow breathing, very low blood pressure, passing more urine than normal and fainting.
For how long do I need to take Tolvaptan 30?
Tolvaptan 30 is used for correction of sodium levels in blood. Though the dose and duration are prescribed by the doctor, Tolvaptan 30 should not be taken for more than 30 days. Once the sodium levels return to normal, it can be stopped after talking to the doctor.
Who should not take Tolvaptan 30?
You should not take Tolvaptan 30 if you have low sodium levels, cannot replace fluids by drinking or if you cannot tell when you are thirsty, dizzy or feeling faint or if your kidneys are not working properly because of excessive loss of fluids. You should also avoid Tolvaptan 30 if your body is not able to make urine, you are allergic to Tolvaptan 30 or if you are on certain medicines which interfere with the working of Tolvaptan 30.
What if you forget to take Tolvaptan Tablet?
If you miss a dose of Tolvaptan 30, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Tolvaptan 30 Tablet Reviews
Tolvaptan 30 is a medicine used in the treatment of low levels of sodium in the blood. It treats low levels of sodium in the blood, which can result from conditions such as heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone (SIADH).
Tolvaptan 30 can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.
Using this medicine may cause few common side effects such as frequent urge to urinate, nocturia (increased urge to urinate during the night), dryness in mouth, increased thirst, nausea, increased blood creatinine, hyperkalemia, and constipation. Let your doctor know if any of these side effects do not go away with time or get worse. Before using this medicine, inform your doctor if you have any problems with your kidneys or liver. While on this medicine, your doctor will closely monitor the sodium levels in your blood. You should also tell your doctor all the other medications you are taking.
Tolvaptan 30 can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.
Using this medicine may cause few common side effects such as frequent urge to urinate, nocturia (increased urge to urinate during the night), dryness in mouth, increased thirst, nausea, increased blood creatinine, hyperkalemia, and constipation. Let your doctor know if any of these side effects do not go away with time or get worse. Before using this medicine, inform your doctor if you have any problems with your kidneys or liver. While on this medicine, your doctor will closely monitor the sodium levels in your blood. You should also tell your doctor all the other medications you are taking.
How Tolvaptan 30 Tablet Works
Tolvaptan 30 is a vasopressin antagonist. It works by blocking the effect of the hormone vasopressin in the body. This increases urine production, reduces the amount of water in the blood and raises the blood sodium level.
How to Use Tolvaptan 30 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolvaptan 30 may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Tolvaptan 30 Tablet
- In Treatment of Low levels of sodium in the blood: Low levels of sodium may be caused due to multiple reasons such as excess of body fluids, heart disease, and kidney problems. There may be many symptoms such as nausea, headache confusion and the person may even need to get hospitalized. Tolvaptan 30 helps to get rid of the excess fluids and retains sodium in the blood. This restores the normal sodium levels in our body and prevents further complications such as memory loss.
Uses of Tolvaptan 30 Tablet
- Treatment of Low levels of sodium in the blood
Tolvaptan 30 Tablet Side Effects
Safety Tips
Pregnancy
CONSULT YOUR DOCTOR
Tolvaptan 30 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Tolvaptan 30 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Tolvaptan 30 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Tolvaptan 30 is safe to use in patients with kidney disease. No dose adjustment of Tolvaptan 30 is recommended.However, the use of Tolvaptan 30 is not recommended in patients with severe kidney disease.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Tolvaptan 30. Please consult your doctor.
Liver
CAUTION
Tolvaptan 30 should be used with caution in patients with liver disease. Dose adjustment of Tolvaptan 30 may be needed. Please consult your doctor.Use of Tolvaptan 30 is not recommended in patients with severe liver disease.
Quick Tips
- Do not take Tolvaptan 30 if you are unable to urinate, if you are unable to tell when you are thirsty, or if you are severely dehydrated.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- You will need to be in a hospital under observation any time you start or restart treatment with Tolvaptan 30.
- It also improves urine flow without causing the body to lose too much sodium as you urinate.
- Take it at the same time everyday. Take it according to the dose and duration prescribed by your doctor.
- Tolvaptan 30 treats low sodium levels in the blood.
- To avoid dehydration, it is best to drink something as soon as you feel thirsty, but avoid alcoholic drinks.
- Inform your doctor if you notice problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, or mood changes.
References
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- Masters SB. Hypothalamic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 659.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1379-80.
- Tolvaptan [Product Label]. Mumbai, Maharashtra: Alkem Labs Limited; 2019.
- ScienceDirect. Tolvaptan.
- Tolvaptan. Otsuka Pharmaceutical Co.; 2009 [revised Apr. 2013]. [Accesses 04 Apr. 2019] (online) Available from:
- PubChem. Tolvaptan.
- Rangarajan B, Binoy V, Hingmire SS, Noronha V. Tolvaptan. South Asian J Cancer. 2014 Jul;3(3):182-4.
- Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC,12th ed. editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 714.