Topise 50mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Arco Pharmaceuticals
Active Ingredient	Topiramate (50mg)
Storage	Store below 30°C
Chemical Class	Dioxolopyrans Derivative
Habit Forming	No
Therapeutic Class	NEURO CNS
Action Class	Sodium channel modulators (AED)
User Rating	4.5
User Reviews	732

FAQ

Is Topise 50mg good for anxiety?

Topise 50mg is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.

What are the serious side effects of Topise 50mg?

Serious side effects of Topise 50mg are rare. The serious effects of Topise 50mg may include glaucoma (difficulty in seeing, eye pain, and blurred vision), kidney stones (sharp pain in your sides or lower back), and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of Topise 50mg could be suicidal thoughts and insufficient sweating (some children taking Topise 50mg may not sweat enough in hot weather, causing their body temperatures to rise).

I am taking valproic acid for fits. Will Topise 50mg interfere with the working of valproic acid? Can this combination be taken?

Topise 50mg does not interfere with the working of valproic acid, but it increases the risk of getting excess levels of ammonia in the blood (hyperammonemia). Increased levels of ammonia in the blood can be dangerous and may cause difficulty in thinking, remembering information, or solving problems. It may also decrease your alertness and make you feel very sleepy with low energy. Immediately inform your doctor if you notice these symptoms. It is important to know that, in rare cases, Topise 50mg alone can cause hyperammonemia.

Can Topise 50mg be used in children?

Yes, Topise 50mg is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraines.

For how long do I need to take Topise 50mg?

The dose and duration of this medicine will depend on your doctor’s advice. Topise 50mg does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.

Since I have started using Topise 50mg people are saying that I have lost weight. Is it because of Topise 50mg or something else for which I should get investigated?

It could be due to Topise 50mg because Topise 50mg commonly causes weight loss probably due to a decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.

What if you forget to take Topise Tablet?

If you miss a dose of Topise 50mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Topise 50mg Tablet Reviews

Topise 50mg is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).

Topise 50mg may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Stopping the medication suddenly without talking to your doctor may cause an increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.

Some of the common side effects of this medicine include nausea, taste change, fatigue, diarrhea, weight loss, loss of appetite, and memory impairment. It may also cause vision problems like myopia or glaucoma, so it is important to get your eyesight checked before you start the treatment and regularly thereafter. You may experience dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Please consult your doctor if these side effects bother you or do not go away.

How Topise 50mg Tablet Works

Topise 50mg is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

How to Use Topise 50mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topise 50mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Topise 50mg Tablet

In Lennox–Gastaut syndrome: Lennox-Gastaut syndrome (LGS) is a rare but severe form of epilepsy that usually starts in early childhood. Affected children may experience several different types of seizures. Topise 50mg helps prevent and control these seizures by decreasing the nerve impulses which cause the seizures.
In Prevention of Migraine: It is not fully established how Topise 50mg helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
In Epilepsy/Seizures: Topise 50mg is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Uses of Topise 50mg Tablet

Prevention of Migraine
Lennox–Gastaut syndrome
Epilepsy/Seizures

Topise 50mg Tablet Side Effects

Safety Tips

Pregnancy ^{CONSULT YOUR DOCTOR}

Topise 50mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Driving ^UNSAFE

Topise 50mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Liver ^CAUTION

Topise 50mg should be used with caution in patients with liver disease. Dose adjustment of Topise 50mg may be needed. Please consult your doctor.

Breast feeding ^{CONSULT YOUR DOCTOR}

Topise 50mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Kidney ^CAUTION

Topise 50mg should be used with caution in patients with kidney disease. Dose adjustment of Topise 50mg may be needed. Please consult your doctor.

Alcohol ^UNSAFE

It is unsafe to consume alcohol with Topise 50mg.

Quick Tips

Limit the use of screen time such as mobile/laptop.
Practice yoga every day.
Take your medication on time.
Get enough sleep at nighttime.
Some healthy tips to prevent seizures:Practice yoga every day.Get enough sleep at nighttime.Limit the use of screen time such as mobile/laptop.Take your medication on time.
Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topise 50mg. This can reduce the risk of kidney stones.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Monitor your weight during treatment with this medicine as it can cause weight gain.

References

Central Drugs Standard Control Organisation (CDSCO).
Topiramate [Prescribing Information]. 2012. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2009.
Stahl SM, editor. Topiramate. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 669-73.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1380-82.
Topiramate. Gurabo, Puerto Rico: Janssen Ortho; 2012.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Topiramate. [Updated 2020 Jan 20].
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 601.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 12.
Topiramate. High Wycombe, Bucks: Janssen-Cilag Ltd.; 1995 [revised 13 Dec. 2017].