Tretosil 20mg Tablet
Product Info
| Prescription required | Yes |
| Marketer | Stelon Biotech Private Limited |
| Active Ingredient | Isotretinoin (20mg) |
| Storage | Store below 30°C |
| Chemical Class | Retinoid |
| Habit Forming | No |
| Therapeutic Class | DERMA |
| Action Class | Retinoids- First generation |
| User Rating | 4.1 |
| User Reviews | 789 |
FAQ
Is the effect of Tretosil 20mg permanent?
It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Tretosil 20mg has shown that the symptoms in the patients with acne may continue to improve following treatment with Tretosil 20mg.
Is Tretosil 20mg a steroid?
No, Tretosil 20mg is a retinoid (vitamin A) which is used to treat severe types of acne.
Why is Tretosil 20mg so dangerous during pregnancy?
If pregnancy occurs during treatment with Tretosil 20mg then, there is an extremely high risk that the baby may be born with severe birth defects.
Does Tretosil 20mg affect male fertility?
No, Tretosil 20mg does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.
Is Tretosil 20mg safe to use?
Tretosil 20mg should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Tretosil 20mg should not be used by pregnant women because it can cause severe birth defects.
What are the long-term side effects of Tretosil 20mg?
A normal course of treatment of Tretosil 20mg is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.
Can Tretosil 20mg cause cancer?
No, there are no reports of Tretosil 20mg causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.
What are the recommended tests during Tretosil 20mg therapy?
Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.
Does Tretosil 20mg damage your liver?
There may be a transient increase in liver enzymes with Tretosil 20mg use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Tretosil 20mg.
What if you forget to take Tretosil Tablet?
If you miss a dose of Tretosil 20mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Tretosil 20mg Tablet Reviews
Tretosil 20mg belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.
Tretosil 20mg should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.
The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.
Tretosil 20mg may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.
Tretosil 20mg should be used in the dose and duration as advised by your doctor. Take it with food, preferably at the same time each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep taking the medicine regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.
The most common side effects include dry skin, rash, and increased liver enzymes. They are not usually serious and often disappear after getting used to the medicine but if they bother you or do not go away, tell your doctor.
Tretosil 20mg may make you more sensitive to sunlight so you should limit your exposure to the sun. It may also make your skin more fragile. Avoid any waxing (hair removal), or laser treatments during treatment. Additionally, it may cause dryness of the mouth, lips, and eyes so drink plenty of water and use a moisturizer. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning pregnancy.
How Tretosil 20mg Tablet Works
Tretosil 20mg is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).
How to Use Tretosil 20mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tretosil 20mg is to be taken with food.
Benefits of Tretosil 20mg Tablet
- In Treatment of Acne: Tretosil 20mg helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.
Uses of Tretosil 20mg Tablet
- Treatment of Acne
Tretosil 20mg Tablet Side Effects
Safety Tips
Liver
UNSAFE
Tretosil 20mg is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Tretosil 20mg. Please consult your doctor.
Driving
UNSAFE
Tretosil 20mg may cause side effects which could affect your ability to drive.Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability.
Pregnancy
UNSAFE
Tretosil 20mg is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Tretosil 20mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Kidney
CAUTION
Tretosil 20mg should be used with caution in patients with kidney disease. Dose adjustment of Tretosil 20mg may be needed. Please consult your doctor.
Quick Tips
- It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
- Do not take Tretosil 20mg if you are pregnant, planning pregnancy or breastfeeding.
- You have been prescribed Tretosil 20mg for the treatment of severe acne.
- Avoid exposure to sunlight while using Tretosil 20mg. Use protective measures such as sunscreen or protective clothing.
- Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
- Take it with food.
References
- Central Drugs Standard Control Organization. Safety guidelines for isotretinoin. 2018.
- Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002.
- Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
- Central Drugs Standard Control Organisation (CDSCO).
- CiplaMed. Isotretinoin [Prescribing Information]. [Last Revised: 29 Nov. 2019].
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
- Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
- Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.