Unifolin 15mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	United Biotech Pvt Ltd
Active Ingredient	Calcium Leucovorin (15mg)
Salt Synonyms	Calcium folinate
Storage	Store below 30°C
Chemical Class	Glutamic acid Derivatives
Habit Forming	No
Therapeutic Class	BLOOD RELATED
Action Class	Cytoprotective agents- methotrexate
User Rating	4.2
User Reviews	520

FAQ

What are some of the laboratory tests conducted before or during the treatment with Unifolin 15mg?

Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Unifolin 15mg. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Unifolin 15mg contains calcium.

How long does it take for Unifolin 15mg to work?

Unifolin 15mg starts acting on the body within 20-30 minutes of oral intake. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What is Unifolin 15mg used for?

Unifolin 15mg is used to prevent harmful effects of methotrexate (a cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Unifolin 15mg is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Unifolin 15mg?

Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

What is megaloblastic anemia?

Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency.

What if you forget to take Unifolin Tablet?

If you miss a dose of Unifolin 15mg, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Unifolin 15mg Tablet Reviews

Unifolin 15mg is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used in the treatment of methotrexate overdose.

Unifolin 15mg can be taken with or without food. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.

It is generally safe medicine to use with no common side effects if taken in the right amount. Your doctor may request regular blood tests to monitor your blood cells and serum methotrexate concentration in the blood.

Before taking it, tell your doctor if have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using, especially phenytoin for your seizures.

How Unifolin 15mg Tablet Works

Unifolin 15mg is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.

How to Use Unifolin 15mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Unifolin 15mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Unifolin 15mg Tablet

In Prevention of Harmful effects of methotrexate: Unifolin 15mg helps protect the body cells against the harmful effects of methotrexate, an anti-cancer medicine. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Unifolin 15mg will prevent the other side effects such as anemia.

Uses of Unifolin 15mg Tablet

Prevention of Harmful effects of methotrexate

Unifolin 15mg Tablet Side Effects

No common side effects seen

Safety Tips

Alcohol ^{CONSULT YOUR DOCTOR}

It is not known whether it is safe to consume alcohol with Unifolin 15mg. Please consult your doctor.

Pregnancy ^{CONSULT YOUR DOCTOR}

Unifolin 15mg may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Liver ^{CONSULT YOUR DOCTOR}

There is limited information available on the use of Unifolin 15mg in patients with liver disease. Please consult your doctor.

Kidney ^{CONSULT YOUR DOCTOR}

There is limited information available on the use of Unifolin 15mg in patients with kidney disease. Please consult your doctor.

Breast feeding ^{CONSULT YOUR DOCTOR}

Information regarding the use of Unifolin 15mg during breastfeeding is not available. Please consult your doctor.

Driving ^SAFE

Unifolin 15mg does not usually affect your ability to drive.

Quick Tips

Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Unifolin 15mg may counteract the antiepileptic effects.
You have been prescribed Unifolin 15mg to reduce the side effects of the medicine methotrexate.