Unigef 250mg Tablet

 Reviews  How to Use  Benefits  Uses  Side Effects

Product Info

Prescription required Yes
Marketer Samarth Life Sciences Pvt Ltd
Active Ingredient Gefitinib (250mg)
Storage Store below 30°C
Chemical ClassQuinazolinamines
Habit FormingNo
Therapeutic ClassANTI NEOPLASTICS
Action ClassTyrosine kinase inhibitors
User Rating4.2
User Reviews334
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FAQ

Question
What if you forget to take Unigef Tablet?
If you miss a dose of Unigef 250mg, skip it and continue with your normal schedule. Do not double the dose.
Answer

Unigef 250mg Tablet Reviews

Unigef 250mg is used in the treatment of non-small cell lung cancer. It is used in patients in which it has spread to other parts of the body, who have abnormal epidermal growth factor receptor (EGFR) genes, and who have not had previous treatment for cancer.

Unigef 250mg should be taken in a dose as recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Your doctor may advice for regular monitoring of liver function while your taking this medicine.


Common side effects include diarrhea, dry skin, loss of appetite, and nausea. Drink plenty of fluids to reduce the risk of side effects. Inform your doctor if any of the side effects bother you or get worse. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor.


Women who are undergoing treatment should use effective contraception method. It is important to avoid pregnancy during the treatment and for a month after completing the course of medicine. Let your doctor also know about all the other medications you are taking.

How Unigef 250mg Tablet Works

Unigef 250mg is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

How to Use Unigef 250mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Unigef 250mg may be taken with or without food, but it is better to take it at a fixed time.

Benefits of Unigef 250mg Tablet

  • In Non-small cell lung cancer: Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Unigef 250mg helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Uses of Unigef 250mg Tablet

  • Non-small cell lung cancer

Unigef 250mg Tablet Side Effects

Item form

Safety Tips

Kidney  CAUTION
Unigef 250mg should be used with caution in patients with severe kidney disease. Dose adjustment of Unigef 250mg may be needed. Please consult your doctor.
Liver  SAFE IF PRESCRIBED
Unigef 250mg is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Unigef 250mg may not be needed in these patients. Please consult your doctor.
Pregnancy  CONSULT YOUR DOCTOR
Unigef 250mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Alcohol  UNSAFE
It is unsafe to consume alcohol with Unigef 250mg.
Breast feeding  CONSULT YOUR DOCTOR
Unigef 250mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving  UNSAFE
Unigef 250mg may cause side effects which could affect your ability to drive.

Quick Tips

  • Unigef 250mg helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
  • Do not take antacids (to reduce the acid level of your stomach) 2 hours before or 1 hour after taking this medicine.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.

References

  1. CiplaMed. Gefitinib [Prescribing Information].
  2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Gefitinib. [Updated 2018 Dec 3].
  3. Gefitinib. Luton, Bedfordshire: AstraZeneca UK Limited; 2009 [revised 23 Apr. 2018].
  4. Central Drugs Standard Control Organisation (CDSCO).
  5. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1734-35.
  6. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 616-17.
  7. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.

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