Xpreza 300mg Tablet
Product Info
| Prescription required | Yes |
| Marketer | Natco Pharma Ltd |
| Active Ingredient | Azacitidine (300mg) |
| Storage | Store below 30°C |
| Chemical Class | Pyrimidine Nucleoside Analogue |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| User Rating | 4.1 |
| User Reviews | 724 |
FAQ
Is Xpreza 300mg chemotherapy?
Yes. Xpreza 300mg is chemotherapy and a cytotoxic drug used in the treatment of various cancers. It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Is Xpreza 300mg a vesicant?
Xpreza 300mg is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Xpreza 300mg into the surrounding tissues from the site of administration) when injected
Does Xpreza 300mg cause hair loss?
No, Xpreza 300mg is not known to cause hair los
Is Xpreza 300mg a cytotoxic drug?
Yes. Xpreza 300mg is a cytotoxic drug.
Xpreza 300mg Tablet Reviews
Xpreza 300mg is used in the treatment of some kinds of blood cancer. It is used for the treatment of adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may be also used to treat other conditions, as determined by the doctor.
Xpreza 300mg can be taken with or without food, but better to have it same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, weakness, nausea, and fever. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.
Xpreza 300mg can be taken with or without food, but better to have it same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, weakness, nausea, and fever. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.
How Xpreza 300mg Tablet Works
Xpreza 300mg is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in leukaemia. This kills the cancer cells and helps in normal maturation and growth of young blood cells in the bone marrow.
How to Use Xpreza 300mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xpreza 300mg may be taken with or without food, but it is better to take it at a fixed time.
Benefits of Xpreza 300mg Tablet
- In Treatment of Myelodysplastic syndrome: Xpreza 300mg is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Xpreza 300mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
- In Blood cancer: Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Xpreza 300mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Xpreza 300mg Tablet
- Treatment of Myelodysplastic syndrome
- Blood cancer
Xpreza 300mg Tablet Side Effects
Safety Tips
Liver
CAUTION
Xpreza 300mg should be used with caution in patients with liver disease. Dose adjustment of Xpreza 300mg may be needed. Please consult your doctor.Use of Xpreza 300mg is not recommended in patients with advanced liver cancer.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xpreza 300mg. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Xpreza 300mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Xpreza 300mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Xpreza 300mg may cause side effects which could affect your ability to drive.Xpreza 300mg can cause side effects such as tiredness and this may affect your ability to drive.
Kidney
CAUTION
Xpreza 300mg should be used with caution in patients with kidney disease. Dose adjustment of Xpreza 300mg may be needed. Please consult your doctor.
Quick Tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 112-13.
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1700.