Zelgor 250mg Tablet

Reviews How to Use Benefits Uses Side Effects

Product Info

Prescription required	Yes
Marketer	Sun Pharmaceutical Industries Ltd
Active Ingredient	Abiraterone Acetate (250mg)
Storage	Store below 30°C
Chemical Class	Androstene Derivative
Habit Forming	No
Therapeutic Class	ANTI NEOPLASTICS
Action Class	Anticancer-others
User Rating	4.3
User Reviews	408

FAQ

Can Zelgor 250mg cure prostate cancer?

Zelgor 250mg does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Zelgor 250mg then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Zelgor 250mg.

Does Zelgor 250mg affect liver?

Zelgor 250mg can cause severe liver problems. In very rare cases, Zelgor 250mg may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.

Why do I need to take prednisolone with Zelgor 250mg?

Your doctor will always prescribe prednisolone with Zelgor 250mg. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Zelgor 250mg.

How to take Zelgor 250mg?

Zelgor 250mg should be taken on an empty stomach with water 1 hour before eating or at least 2 hours after eating. Taking it with food may cause increased and variable levels of Zelgor 250mg in your blood which can be harmful. Remember not to crush or chew the tablet.

How frequently should the liver investigations be done?

Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Zelgor 250mg.

Is Zelgor 250mg a chemotherapy drug?

Zelgor 250mg is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Zelgor 250mg stops your body from making testosterone. This can slow down the growth of prostate cancer.

What if you forget to take Zelgor Tablet?

If you miss a dose of Zelgor 250mg, skip it and continue with your normal schedule. Do not double the dose.

Zelgor 250mg Tablet Reviews

Zelgor 250mg is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Zelgor 250mg should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, and fatigue. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.

Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

How Zelgor 250mg Tablet Works

Zelgor 250mg is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

How to Use Zelgor 250mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zelgor 250mg is to be taken empty stomach.

Benefits of Zelgor 250mg Tablet

In Prostate cancer: Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Zelgor 250mg decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Uses of Zelgor 250mg Tablet

Prostate cancer

Zelgor 250mg Tablet Side Effects

Safety Tips

Pregnancy ^UNSAFE

Zelgor 250mg is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Driving ^SAFE

Zelgor 250mg does not usually affect your ability to drive.

Liver ^CAUTION

Zelgor 250mg should be used with caution in patients with liver disease. Dose adjustment of Zelgor 250mg may be needed. Please consult your doctor.

Alcohol ^{CONSULT YOUR DOCTOR}

It is not known whether it is safe to consume alcohol with Zelgor 250mg. Please consult your doctor.

Kidney ^CAUTION

Zelgor 250mg should be used with caution in patients with severe kidney disease. Dose adjustment of Zelgor 250mg may be needed. Please consult your doctor.

Breast feeding ^UNSAFE

Zelgor 250mg is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Quick Tips

Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Zelgor 250mg treats prostate cancer that has spread to other parts of the body.
It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
It is usually taken with another medicine called prednisolone to reduce unwanted side effects.

References

Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017.
Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016].
Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011.
Central Drugs Standard Control Organisation (CDSCO).
CiplaMed. Abiraterone Acetate [Prescribing Information].
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.