Zole-R 20 Tablet
Product Info
Prescription required | Yes |
Marketer | Raffles Pharmaceuticals |
Active Ingredient | Rabeprazole (20mg) |
Storage | Store below 30°C |
Chemical Class | Sulfinylbenzimidazole Derivative |
Habit Forming | No |
Therapeutic Class | GASTRO INTESTINAL |
Action Class | Proton pump inhibitors |
User Rating | 4.3 |
User Reviews | 571 |
FAQ
What is the best time to take Zole-R 20?
It is best to take Zole-R 20 before your breakfast. If you are taking two doses, take it in the morning and evening. Zole-R 20 is more effective when it is taken an hour before your food.
What is Zole-R 20 used for?
Zole-R 20 is used for the treatment of stomach and intestinal ulcers (gastric and duodenal ulcers), reflux esophagitis, or gastroesophageal reflux disease (GERD). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms. Zole-R 20 also prevents acidity associated with the use of painkillers and stress ulcers in critically ill people. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES).
Can I take antacids along with Zole-R 20?
Yes, you can take antacids along with Zole-R 20. Take it 2 hours before or after you take Zole-R 20.
How is Zole-R 20 useful in the treatment of H. pylori infection?
Zole-R 20 is used along with antibiotics for the treatment of H.Pylori infection. It works by decreasing stomach acid volume and decreasing breakdown and washout of antibiotics leading to an increased antibiotic concentration and tissue penetration. It also helps in symptomatic relief by decreasing associated acidity, reflux, and heartburn.
Can long term use of Zole-R 20 cause magnesium deficiency?
Long-term use of Zole-R 20 can lower magnesium levels in patients taking multiple daily doses for 3 months or longer. Get your magnesium levels checked at regular intervals. Tell your doctor if you experience seizures (fits), dizziness, abnormal or fast heartbeat, jitteriness, jerking movements or shaking (tremors), muscle weakness, spasms of the hands and feet, cramps, muscle aches.
Can I stop taking Zole-R 20 if I feel better?
No, do not stop taking Zole-R 20 before completing the full course of treatment. You will start to feel better before your treatment is complete.
What dietary changes should I make to get relief from acidity?
Zole-R 20 is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. It also helps to cut down on caffeinated drinks such as tea, coffee, and cola. Alcohol intake should also be avoided as it may worsen your symptoms.
Can I take alcohol with Zole-R 20?
No, alcohol intake is not advised with Zole-R 20. Alcohol itself does not affect the working of Zole-R 20, but it can increase acid production. This may further cause worsening of your symptoms.
Is it safe to use Zole-R 20 for a long period of time?
Zole-R 20 should be used for as long as it has been prescribed by your doctor. Zole-R 20 is usually considered to be safe when taken in the recommended dose and duration. If Zole-R 20 is used for more than 3 months, certain long-term side effects may be seen. The most important of these is low magnesium levels in your blood, making you feel tired, confused, dizzy, shaky, or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections, subacute cutaneous lupus erythematosus, osteoporosis, and vitamin B12 deficiency.
What other lifestyle changes should I make to get maximum benefit of Zole-R 20?
You make see better results if you make certain dietary and lifestyle changes while taking Zole-R 20. Exercise regularly and eat healthily. You can consult your dietician to get a diet chart that suits you best. Eat at least 3 hours before sleeping to reduce the chances of aggravation of your symptoms at night. You should avoid spicy and fatty foods while taking this medicine. Refrain from caffeinated drinks such as tea, coffee, and cola. Alcohol intake and smoking should also be avoided as they may worsen your symptoms.
Does Zole-R 20 cause bone problems?
Yes, long-term use of Zole-R 20 can cause thinning of bones, which is called osteoporosis. Zole-R 20 decreases the calcium absorption leading to calcium deficiency and increases the risk of bone fractures of the hip, wrist, or spine. Take an adequate amount of calcium in your diet or take the supplements as advised by your doctor to avoid any bone problems.
How long does it take for Zole-R 20 to work?
Zole-R 20 starts working within an hour of taking it and shows maximum benefit within two to four hours. You should start feeling better within 2 to 3 days but it may take up to 4 weeks to relieve your symptoms significantly.
Can I take Zole-R 20 with vitamin D?
Yes, vitamin D can be taken along with Zole-R 20. Vitamin D is generally advised to be taken as a supplement with Zole-R 20 as the long-term use of Zole-R 20 decreases the absorption of calcium and may lead to calcium deficiency. This can lead to osteoporosis (thinning of bones) and increase the risk of bone fractures like hip, wrist, and spine fractures. Please consult your doctor to know about ways to prevent this.
What if you forget to take Zole-R Tablet?
If you miss a dose of Zole-R 20, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Zole-R 20 Tablet Reviews
Zole-R 20 is a medicine that reduces the amount of acid produced in your stomach. It is used in the treatment of acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, and Zollinger-Ellison syndrome. It provides relief from symptoms and promotes healing.
Zole-R 20 medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying condition and how you respond to the medicine. Try to take it regularly at the same time each day as advised by your doctor. You should keep on taking it as prescribed even if your symptoms disappear quickly. You may be able to help improve your symptoms by eating smaller meals more often and avoiding caffeinated drinks like tea and coffee, and spicy or fatty foods.
This medicine's most common side effects include nausea, vomiting, headache, dizziness, flatulence, diarrhea, and stomach pain. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. Long-term use (more than 1 year) may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Low blood magnesium levels (hypomagnesemia) have been seen in some people taking this medicine for 3 months or more. This may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this.
Zole-R 20 is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.
Zole-R 20 medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying condition and how you respond to the medicine. Try to take it regularly at the same time each day as advised by your doctor. You should keep on taking it as prescribed even if your symptoms disappear quickly. You may be able to help improve your symptoms by eating smaller meals more often and avoiding caffeinated drinks like tea and coffee, and spicy or fatty foods.
This medicine's most common side effects include nausea, vomiting, headache, dizziness, flatulence, diarrhea, and stomach pain. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. Long-term use (more than 1 year) may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Low blood magnesium levels (hypomagnesemia) have been seen in some people taking this medicine for 3 months or more. This may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this.
Zole-R 20 is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.
How Zole-R 20 Tablet Works
Zole-R 20 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
How to Use Zole-R 20 Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zole-R 20 is to be taken empty stomach.
Benefits of Zole-R 20 Tablet
- In Treatment of Zollinger-Ellison syndrome: Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Zole-R 20 By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.
- In Treatment of Peptic ulcer disease: Zole-R 20 belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes, preventing further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.
- In Treatment of Gastroesophageal reflux disease (Acid reflux): GERD is a chronic (long-term) condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Zole-R 20 belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Uses of Zole-R 20 Tablet
- Treatment of Gastroesophageal reflux disease (Acid reflux)
- Treatment of Peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
Zole-R 20 Tablet Side Effects
Safety Tips
Driving
UNSAFE
Zole-R 20 may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Breast feeding
CONSULT YOUR DOCTOR
Zole-R 20 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Kidney
SAFE IF PRESCRIBED
Zole-R 20 is safe to use in patients with kidney disease. No dose adjustment of Zole-R 20 is recommended.
Pregnancy
CONSULT YOUR DOCTOR
Zole-R 20 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Alcohol
CAUTION
Caution is advised when consuming alcohol with Zole-R 20. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Zole-R 20 is safe to use in patients with liver disease. No dose adjustment of Zole-R 20 is recommended.
Quick Tips
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Avoid eating late at night or before bedtime.
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- It is a well-tolerated medicine and provides relief for a long time.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Zole-R 20 can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Some healthy tips to prevent acidity from happening:Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.Avoid alcohol and smoking.Avoid eating late at night or before bedtime.
- Avoid alcohol and smoking.
References
- CiplaMed. Rabeprazole sodium [Prescribing Information].
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rabeprazole. [Updated 2019 Jun 3].
- Central Drugs Standard Control Organisation (CDSCO).
- Rabeprazole. Charlotte, NC: FSC Laboratories; 1999 [revised Dec. 2014].
- Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011.