Peg-Joxorub Solution for Infusion
Product Info
| Prescription required | Yes |
| Marketer | Jodas Expoim |
| Active Ingredient | Doxorubicin (Liposomal) (2mg/ml) |
| Chemical Class | Anthracycline Derivative |
| Habit Forming | No |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| User Rating | 4.4 |
| User Reviews | 465 |
FAQ
How does doxorubicin work?
Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell.
What is liposomal doxorubicin?
The molecules of doxorubicin are coated in a fatty capsule called as liposome. This liposome protects the body and allows the doxorubicin to remain in the blood circulation for a longer duration. This means that more amount of drug can be delivered to the cancer cells with less side effects.
Peg-Joxorub Solution for Infusion Reviews
Peg-Joxorub Solution for is used in the treatment of some kinds of cancer. It is also used in the treatment of breast cancer, where there is an increased cardiac risk. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
Peg-Joxorub Solution for can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment.
The most common side effects of this medicine include nausea, vomiting, rash, weakness, low blood platelets. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lead to problems with your blood, liver or heart. Your doctor will advise you regular blood tests to check for these.
Before taking this medicine, let your doctor know if you have liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.
Peg-Joxorub Solution for can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment.
The most common side effects of this medicine include nausea, vomiting, rash, weakness, low blood platelets. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lead to problems with your blood, liver or heart. Your doctor will advise you regular blood tests to check for these.
Before taking this medicine, let your doctor know if you have liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.
How Peg-Joxorub Solution for Infusion Works
Peg-Joxorub Solution for is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.
How to Use Peg-Joxorub Solution for Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Benefits of Peg-Joxorub Solution for Infusion
- In Cancer: Peg-Joxorub Solution for helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Peg-Joxorub Solution for kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Uses of Peg-Joxorub Solution for Infusion
- Cancer
Peg-Joxorub Solution for Infusion Side Effects
Safety Tips
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Peg-Joxorub Solution for during breastfeeding is not available. Please consult your doctor.
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Peg-Joxorub Solution for. Please consult your doctor.
Kidney
SAFE IF PRESCRIBED
Peg-Joxorub Solution for is safe to use in patients with kidney disease. No dose adjustment of Peg-Joxorub Solution for is recommended.Caution is advised in patients with severe kidney disease as the information available is limited for use of this medicine in these patients.
Pregnancy
CONSULT YOUR DOCTOR
Peg-Joxorub Solution for is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Liver
CAUTION
Peg-Joxorub Solution for should be used with caution in patients with liver disease. Dose adjustment of Peg-Joxorub Solution for may be needed. Please consult your doctor.Use of Peg-Joxorub Solution for is not recommended in patients with severe liver disease.
Driving
UNSAFE
Peg-Joxorub Solution for may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Quick Tips
- It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
- Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
- Peg-Joxorub Solution for helps treat cancer of the breast, blood, and ovaries.
- It may make you feel tired or sleepy. Do not drive or do anything that requires mental focus until you know how it affects you.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
- Inform your doctor if you notice sores, discolouration or any discomfort in your mouth.
References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
- Drugs.com. Doxorubicin Pregnancy and Breastfeeding Warnings.
- Central Drugs Standard Control Organisation (CDSCO).
- Doxorubicin hydrochloride liposome. Bedford, Ohio: Ben Venue Laboratories, Inc.; 1995 [revised May 2007]. (online) Available from:
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.